9 citations
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January 2017 in “Food & Nutrition Research” In this study, rice bran mineral extract increased expression of anagen-related proteins and decreased inflammatory markers in human dermal papilla cells, suggesting potential for hair growth enhancement and prevention of hair loss.
June 2025 in “Korean Journal of Pharmacognosy” In a mouse model, this study reported that the compound isoalantolactone significantly improved hair growth and thickness, suggesting its potential as a treatment for hair loss.
54 citations
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April 2019 in “Journal of cellular physiology” In this study, miR-218-5p was found to enhance hair shaft growth and positively regulate the Wnt signaling pathway by targeting SFRP2 during skin and hair follicle development.
10 citations
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May 2020 in “Journal of Dermatological Treatment” This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.
1 citations
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March 2024 in “Cellular and Molecular Biology” In this study, researchers observed that Zibai ointment promoted chronic wound healing in rats by influencing the bFGF/Wnt/β-Catenin signaling pathway, demonstrating a higher wound healing rate compared to other treatments.
July 2026 in “Journal of Investigative Dermatology” Tanshinone Capsule may help regrow hair by boosting specific cell signals.
September 2023 in “World Rabbit Science” In this study using Angora rabbits, researchers found that the FRZB gene inhibits hair follicle development by modulating the Wnt/β-catenin signaling pathway, affecting the expression of various genes related to this pathway and altering cell proliferation and apoptosis.
July 2023 in “Current Issues in Molecular Biology” This study found that escin acts as a natural agonist of the Wnt/β-catenin signaling pathway in cultured human dermal papilla cells by promoting the degradation of GSK-3β, highlighting its potential therapeutic use for conditions like androgenetic alopecia and vitiligo.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and move by activating certain cell pathways.
October 2022 in “International Journal of Molecular Sciences” This study found that collagen peptides from Mozambique tilapia significantly promoted hair regrowth and increased the proliferation of hair growth factors in vitro and in vivo, suggesting potential as supplements for hair loss prevention.
March 2023 in “Chemical biology & drug design” This study found that 8% Panax notoginseng saponins may promote hair follicle growth in C57BL/6J mice, potentially through the Wnt/β-catenin signaling pathway.
April 2024 in “Journal of microbiology and biotechnology” The authors will correct the table to show the right antibody information.
45 citations
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April 2016 in “Journal of Dermatological Science” This study found that the Wnt/β-catenin signaling pathway activates melanocyte stem cells, promoting hair follicle regeneration both in vitro and in vivo.
43 citations
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September 2017 in “Lasers in Surgery and Medicine” This study found that LED light irradiation induced proliferation and migration of human outer root sheath cells, potentially through the stimulation of the Wnt/β-catenin and ERK signaling pathways.
23 citations
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January 2020 in “Frontiers in Pharmacology” In this study, DHT was observed to have varying effects on hair follicle growth and related protein expression depending on concentration, with the Wnt/β-catenin pathway potentially playing a significant role.
14 citations
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April 2021 in “International journal of molecular sciences” This study found that human hematopoietic mesenchymal stem cells increased the viability and migration of human outer root sheath cells in an in vitro alopecia areata model, involving Wnt/β-catenin and JAK/STAT pathways.
9 citations
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October 2013 in “Journal of Investigative Dermatology” This study found that the OVOL1 gene in mouse neonatal dermal cells is crucial for hair follicle neogenesis, suggesting it plays a significant role in maintaining trichogenicity.
7 citations
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March 2022 in “Molecules” This study found that 5-bromo-3,4-dihydroxybenzaldehyde (BDB) promoted hair growth in rat vibrissa follicles by activating Wnt/β-catenin and autophagy pathways and inhibiting the TGF-β pathway in dermal papilla cells.
6 citations
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February 2023 in “Genes” This study found that overexpression of the CUX1 protein promotes proliferation of Hu sheep dermal papilla cells and affects key genes in the Wnt/β-catenin signaling pathway.
5 citations
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October 2024 in “International Journal of Molecular Sciences” This study observed that piperonylic acid activated key signaling pathways in dermal papilla cells and increased hair growth markers, and a clinical trial showed users of a piperonylic acid formulation had more hair than those using a placebo, suggesting its potential for treating hair loss.
27 citations
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May 2017 in “Marine Drugs” This study found that Undariopsis peterseniana extract may promote hair growth by activating specific cellular pathways, suggesting potential for treating alopecia.
2 citations
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May 2022 in “Journal of trace elements in medicine and biology” This study found that administering lower doses of sodium pentaborate pentahydrate increased hair growth in rats via specific molecular pathways, while a higher dose suppressed these pathways and impaired hair growth.
May 2026 in “Animal Bioscience” This study found that m6A-circHECA enhances the differentiation of stem cells into hair follicle lineages in cashmere goats by sequestering miR-449a-5p, boosting LEF1 gene expression, and activating the Wnt/β-catenin pathway.
January 2026 in “Journal of Ethnopharmacology” This study found that naringin, a natural flavonoid, significantly improved hair growth in mice by activating the Wnt/β-catenin pathway, with the 4% concentration showing comparable efficacy to 5% minoxidil, suggesting naringin as a promising alternative for alopecia treatment.
November 2025 in “Journal of Microbiology and Biotechnology” In this study, combining Botulinum toxin type A with Platelet-rich plasma was found to enhance hair follicle growth and reconstruction, potentially through inflammation reduction and activation of the Wnt/β-catenin pathway via STMN1 protein modulation.
October 2023 in “Current Issues in Molecular Biology” In this study, researchers observed that the YH complex, made from Astragalus membranaceus and Cinnamomum cassia, promoted hair regrowth and increased hair shaft thickness in mice, potentially through increased growth factors and Wnt/β-catenin signaling, suggesting its use for treating various forms of hair loss.
This study found that garlic exosomes induced hair growth in rats by increasing anagen follicle counts and activating multiple signaling pathways, including Wnt-1, β-catenin, and TGF-β1.
June 2023 in “Food frontiers” In this animal study, researchers observed that ginsenoside CK significantly reduced hair loss, improved sexual organ health, and encouraged hair growth in mice with androgenetic alopecia by modulating key signaling pathways and normalizing hormone metabolism, highlighting its potential as a therapeutic agent.
November 2022 in “Journal of Investigative Dermatology” This study found that a lotion containing specific plant extracts significantly increased the number of anagen hairs and the anagen/telogen ratio in subjects with androgenetic alopecia after three months of use.
January 2016 in “프로그램북(구 초록집)” In this study, LED irradiation was found to promote hORSC proliferation and stimulate the Wnt5a/β-catenin and ERK signaling pathways, suggesting a potential mechanism for hair growth.