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Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.

DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.

Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.

3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Genes related to calcium signaling and lipid metabolism are important for curly hair in Mangalitza pigs.

Melatonin increased the activity of a hair growth gene in Cashmere goats.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.

The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Methyl vanillate spray increases hair count and hair mass in women with hair loss.

The extract reduced sebum production and promoted hair growth.

Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.

Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.

GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.

Trichostatin A helps restore hair-growing ability in skin cells used for hair regeneration.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

Timosaponin BII, a plant extract, was found to promote hair growth in mice, similarly to minoxidil.

Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.

Stopping S100A3 activity slows down hair growth in mice.