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600-630 / 1000+ resultsresearch Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
research Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling
A form of vitamin E promotes hair growth by activating a specific skin pathway.
![Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1](/images/research/d8d8b765-cdaa-4308-b645-1fba427dcee7/small/36196.jpg)
research Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
![Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation](/images/research/8616fe2d-7045-4f60-a7f4-e60ccaca4aa6/small/26150.jpg)
research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
![Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts](/images/research/112749e6-9434-443c-be2f-13d61b56e8b8/small/26120.jpg)
research Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
![Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis](/images/research/a9b3c3a8-9b4c-42aa-8644-a14fda3cfbdf/small/12622.jpg)
research Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis
Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
![Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from Cashmere Goats](/images/research/60a4638b-d74f-4630-a5be-e96a611f3f2e/small/16583.jpg)
research Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from Cashmere Goats
The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.
![Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis](/images/research/605717bb-ec49-4dc1-b2b6-b3b0cfc9e210/small/19247.jpg)
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
![Region-specific reversal of epidermal planar polarity in the <i>rosette</i> fancy mouse](/images/research/4ba6fad8-36db-41b2-97b2-e7cbc60b30b9/small/30994.jpg)
research Region-specific reversal of epidermal planar polarity in the rosette fancy mouse
Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
![A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia](/images/research/95fa23d2-f289-40ba-a9d0-d5ae22896e14/small/3922.jpg)
research A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia
PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.
![Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration](/images/research/4dc60f0c-0d69-4d1f-bd80-cfcbf0072e5d/small/19235.jpg)
research Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
![Roles of Wnt7a in embryo development, tissue homeostasis, and human diseases](/images/research/c37f2ace-1d84-426d-8231-769309f3bc52/small/19337.jpg)
research Roles of Wnt7a in embryo development, tissue homeostasis, and human diseases
Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
![Estrogen modulates mesenchymal-epidermal interactions in the adult nipple](/images/research/961acac0-09c6-4a68-8a30-a351d30174b5/small/19573.jpg)
research Estrogen modulates mesenchymal-epidermal interactions in the adult nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
![TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling](/images/research/b71135fb-3f1b-422c-a38e-887174627d74/small/36746.jpg)
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
![Treatment of MSCs with Wnt1a-conditioned medium activates DP cells and promotes hair follicle regrowth](/images/research/50623562-5a3c-49c2-a53f-705321d150c5/small/14385.jpg)
research Treatment of MSCs with Wnt1a-conditioned medium activates DP cells and promotes hair follicle regrowth
Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
![Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair](/images/research/d22892c6-a26b-44eb-ab2c-11e326ca3532/small/19787.jpg)
research Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair
Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
research Erbium: YAG laser (2,940 nm) treatment stimulates hair growth through upregulating Wnt 10b and β-catenin expression in C57BL/6 mice.
A specific laser treatment can promote hair growth in mice by increasing certain protein levels.
![Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway](/images/research/f3cb6a5d-36e7-4767-b0b6-306d4bffa630/small/25741.jpg)
research Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway
Caffeine can damage hearing cells and affect hearing recovery after ear trauma.
![New developments in stem cell biology and therapy. meeting report from the working group of the German Society for Hematology and Oncology](/images/research/5482b8aa-b517-447a-b357-2242cc2a16b3/small/20021.jpg)
research New developments in stem cell biology and therapy. meeting report from the working group of the German Society for Hematology and Oncology
The meeting highlighted important advances in stem cell research and its potential for creating new medical treatments.
![Hair Thickness Growth Effect of Adenosine Complex in Male-/Female-Patterned Hair Loss via Inhibition of Androgen Receptor Signaling](/images/research/261b9dd5-d574-4b76-8c95-9eec9253a76b/small/37147.jpg)
research Hair Thickness Growth Effect of Adenosine Complex in Male-/Female-Patterned Hair Loss via Inhibition of Androgen Receptor Signaling
Adenosine complex helps increase hair thickness and density in hair loss.
![Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia](/images/research/87f962c8-3dde-4ce5-bd90-156876843e23/small/16462.jpg)
research Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia
The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.
![WNT10B (wingless-type MMTV integration site family)](/images/research/b3743705-9dd2-4307-8085-1d185e657a5d/small/19401.jpg)
research WNT10B (wingless-type MMTV integration site family)
WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
![Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology](/images/research/8e323f49-791d-4d97-b9d0-fee9428e4ff1/small/12883.jpg)
research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology
Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
![<scp>YAP</scp> and <scp>TAZ</scp> are essential for basal and squamous cell carcinoma initiation](/images/research/90e50b67-5543-43d1-bdac-2f591d97adb8/small/19423.jpg)
research YAP and TAZ are essential for basal and squamous cell carcinoma initiation
YAP and TAZ proteins are necessary for the development of two types of skin cancer.
![Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44](/images/research/5f9e53fd-c639-49d0-abb0-05eadcf71170/small/12205.jpg)
research Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44
Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
![TGF‐β<sub>2</sub> is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis](/images/research/7886a053-45d8-414f-9112-1031027daae3/small/30923.jpg)
research TGF‐β2 is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
![Congenital hair loss disorders: Rare, but not too rare](/images/research/0d301843-9bce-4c17-b919-72dcf83adb63/small/26111.jpg)
research Congenital hair loss disorders: Rare, but not too rare
Some hair loss disorders are caused by genetic mutations affecting hair growth.
![Ectodysplasin research—Where to next?](/images/research/f1140feb-322d-4912-a4d1-6d08f9d6a0c9/small/18818.jpg)
research Ectodysplasin research—Where to next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
![Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation](/images/research/28c4a79f-6e9b-45bf-a9a1-a41e84bae463/small/19580.jpg)
research Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation
Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.