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Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

A protein called sFRP4 can partly inhibit hair growth.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Excess androgens may cause PCOS, not just be a symptom.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.