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Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

The skin and thymus develop similarly to protect and support immunity.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.

Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Using skin stem cells and certain molecules might lead to scar-free skin healing.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Smoking increases early hair loss risk in men; quitting may help prevent it.

Chicken feather gene mutation helps understand human hair disorders.