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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Stem cell self-renewal is complex and needs more research for full understanding.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Muscles and nerves that cause goosebumps also help control hair growth.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Pannexin 3 is important for bone formation and the development of bone cells.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.

Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.

Adiponectin may stimulate hair growth and could be a potential treatment for promoting hair growth.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Vitamin D and calcium are important for quick and effective skin wound healing.

The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.

Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.

Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.

Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.