research Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice
Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.
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research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research Emerging Treatments in Alopecia
New alopecia treatments aim for better results and fewer side effects.
research GLI2-Specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
GLI2 increases follistatin production in human skin cells.
research Oncogenic Senescence: A Multi-Functional Perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
research Dormancy in the Stem Cell Niche
Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
research Conventional and Novel Stem Cell-Based Therapies for Androgenic Alopecia
Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
research Bone vs. Fat: Embryonic Origin of Progenitors Determines Response to Androgen in Adipocytes and Osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research Alteration of Skin Wound Healing in Keratinocyte-Specific Mediator Complex Subunit 1 Null Mice
MED1 affects skin wound healing differently in young and old mice.
research LncRNA-000133 from Secondary Hair Follicle of Cashmere Goat: Identification, Regulatory Network, and Its Effects on Inductive Property of Dermal Papilla Cells
A newly found RNA in Cashmere goats may play a role in hair growth and development.
research Vitamin D Receptor Gene Polymorphism in Chronic Telogen Effluvium: A Case-Control Study
Certain gene variations in the Vitamin D receptor may increase the risk of chronic hair loss.
research Hair Growth Activity of Three Plants of the Polynesian Cosmetopoeia and Their Regulatory Effect on Dermal Papilla Cells
Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.
research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Biology of Melanocytes in Mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research Hair Growth Is Promoted in Mouse Dorsal Skin by a Mixture of Platycladus Orientalis Leaf Extract and Alpha-Terpineol by Increasing Growth Factors and Wnt3/β-Catenin
A mix of Platycladus orientalis leaf extract and alpha-terpineol helps mice grow hair by increasing growth factors and cell growth.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Treat Androgenetic Alopecia With Antiandrogens And Other Pharmacological And Non-Pharmacological Interventions
Use antiandrogens and other treatments for hair loss.
research The Relationship Between Keratin 18 and Epithelial-Derived Tumors: As a Diagnostic Marker, Prognostic Marker, and Its Role in Tumorigenesis
Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.
research The G-Protein Coupled Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research MiR-133a-3p and MiR-145-5p Co-Promote Goat Hair Follicle Stem Cell Differentiation by Regulating NANOG and SOX9 Expression
miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.
research Predisposing and Overall Effects of Reproductive Hormones on Breast Cancer: A Review
Reproductive hormones play a crucial role in breast cancer development and treatment challenges.
research Connecting Signaling Dynamics With Cell Fates In Live Mice
Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
research Dynamic Morphogen-p63 Chromatin Interactions That Guide Epigenetic Changes and p63 Activity in Surface Ectoderm Commitment
The study found that p63 needs signals from morphogens to help skin cells differentiate properly.
research Functional Mapping of the Mouse Hairless Gene Promoter Region
Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
research Cutaneous Overexpression of Cyclooxygenase-2 Models Androgenetic Alopecia in Adult Mice
Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification
Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.
research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
research Single-Cell Analysis Reveals Fibroblast Heterogeneity and Myeloid-Derived Adipocyte Progenitors in Murine Skin Wounds
The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.