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This review examines the interaction between hedgehog and Wnt/β-catenin signalling in hair follicles and basal cell carcinoma, linking Hh pathway inhibition to both tumor regression and alopecia.

This review discusses molecular signaling pathways and nutritional factors influencing feather growth and regeneration in poultry and offers no new results; the authors suggest these insights may guide strategies for producing superior plumage.

This review article analyzes the role of the WNT signaling pathway in skin development, wound healing, and mechanical stretching, emphasizing its importance in understanding and potentially advancing treatments for skin-related diseases.

In this study, researchers found that overexpression of CRABP2 enhanced the proliferation of dermal papilla cells in Hu sheep through activation of the Wnt/β-catenin pathway, even when the pathway was inhibited.

This review discusses the similarities between wound healing and embryonic development, focusing on signaling pathways and their potential for developing new wound healing strategies, and reports no new clinical results.

In this study, researchers performed a genome-wide characterization of the Wnt gene family in domestic donkeys, identifying 19 genes and highlighting their evolutionary conservation among mammals, along with tissue-specific expression patterns potentially linked to reproductive regulation and tissue homeostasis.

This review synthesizes recent research on how Wnt signaling regulates skin, hair follicle, and nail regeneration, highlighting its compartment-specific roles and discussing targeted strategies for treating conditions like alopecia, chronic wounds, and skin cancer.

This review discusses the roles and characteristics of skin stem cells, their niches, and signaling pathways in skin maintenance, aging, and cancer, highlighting their potential in therapeutic applications but presenting no new clinical findings.

In this study, overexpression of Wnt5a in mice was associated with the elongation of the telogen stage and inhibition of hair growth initiation, suggesting Wnt5a's role in maintaining hair follicle quiescence.

This review discusses hair follicle stem cells for wound healing and reports no new clinical results, noting their potential but emphasizing the need for further understanding and safety in clinical applications.

This study found that Wnt5a suppresses β-catenin signaling, inhibiting the transition of hair follicles from the telogen to anagen phase.

This forum article in BMC Biology discusses evolving views on the concept of the stem cell niche, highlighting varied mechanisms and the need for better understanding of the niche's roles and functions.

This study found that Smad7 perturbs hair follicle development while promoting sebaceous gland formation by antagonizing Wnt/β-catenin signaling in transgenic mice.

This review discusses the genetic factors involved in hair follicle morphogenesis and cycling and reports no new clinical results; it emphasizes the role of genes in hereditary hair diseases.

This review explores embryonic epidermal development and discusses key molecular regulators and roles of the sub-epidermal mesenchyme, but reports no new experimental results.

This review examines PAK4 signaling pathways in prostate cancer, Parkinson's disease, and melanogenesis, focusing on the potential role of the PAK4-CREB axis, without reporting new clinical results.

This mini-review discusses human hair follicle development and summarizes genetic disorders linked to abnormalities in hair follicle morphogenesis, structure, or regeneration, but reports no new experimental results.

In this study, researchers found that intestine-derived human alpha defensin 5 enhances wound healing, reduces bacterial load, and promotes hair growth in murine burn wound beds by increasing LGR stem cell migration.

This study demonstrated that topical oleuropein induced hair growth in mice by activating the Wnt10b/β-catenin signaling pathway and increasing expression of several growth-related genes in skin tissue.

This study identified the Hairless (Hr) gene-encoded protein as a corepressor that plays a crucial role in maintaining skin and hair by regulating epithelial stem cell differentiation and gene expression via chromatin remodeling, which may impact both development and disease.

This study found that Runx1 in hair follicle stem cells modulates lipid metabolism, impacting membrane organization and enhancing signal transduction for cell proliferation in both normal and cancer epithelial cells.

This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.

This study found that quercitrin, a natural compound, enhances Wnt/β-catenin signaling and may help mitigate synapse loss and memory impairment in Alzheimer's models.

This study found that proteins secreted by early-passage dermal papilla cells, including SDF1, MMP3, biglycan, and LTBP1, may play significant roles in hair follicle regeneration.

In this study, researchers discovered that ROR2, a Wnt receptor, plays a crucial role in regulating hair follicle stem cell self-renewal and maintenance, compensating for the absence of β-catenin.

This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.

This study found that Pannexin 3 plays a crucial role in skin development by regulating the transcription factor Epiprofin, affecting keratinocyte differentiation and hair follicle regeneration in mice.

This study found that ISX9 may activate the Wnt/β-catenin signaling pathway and holds potential as a therapeutic agent for treating alopecia.

This review discusses the role of the Wnt/β-catenin pathway in skin wound repair and explores how photobiomodulation may affect chronic wound healing, but it reports no new clinical results.

This review explores the regenerative potential of hair follicles and their role in complete skin regeneration, emphasizing the influence of mechanical factors and niche signaling pathways on hair growth and loss.