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Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Nerves are crucial for the regeneration of various body parts in many animals.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Lactate production is important for activating hair growth stem cells.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Researchers created human hair follicles using a new method that could help treat hair loss.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Male pattern baldness involves genetics, hormones, and needs better treatments.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

A wearable device using electric stimulation can significantly improve hair growth.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.