Search

everythinglearnresearchcommunity

for

Search:↓

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.

Different types of stem cells help maintain and heal skin.

Skin organoids are a promising new model for studying human skin development and testing treatments.

MED1 affects skin wound healing differently in young and old mice.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

New effective scar treatments are urgently needed due to the current options' limited success.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Advanced human skin models improve drug development and could replace animal testing.

Keratins are important for skin cell health and their problems can cause diseases.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Good feather growth in poultry needs the right balance of proteins, amino acids, minerals, and vitamins.

Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.

Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.

Using special RNA to target a mutant gene fixed hair problems in mice.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The gene Msx2 is crucial for hair follicle regeneration during wound healing.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Researchers successfully transplanted hair follicles in mice, which survived well and helped in wound healing.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Gray hair may be caused by lower antioxidant activity in hair cells.

A specific group of skin stem cells was found to help maintain hair follicle cells.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.