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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.

Activating β-catenin in certain skin cells speeds up hair growth in mice.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Finasteride affects prostate weights and pituitary activity differently with age.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.

Plant root hair growth is mainly controlled by hormones like auxin and ethylene, which promote growth, while others like brassinosteroid inhibit it.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.