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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

Vitamin D and calcium are essential for normal hair growth.

Light can turn on hair growth cells through a nerve path starting in the eyes.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

New ginseng compounds may help treat degenerative diseases.

CCDC22 and CCDC93 are essential for root and root hair growth in Arabidopsis.

Eating fewer calories may slow skin aging and improve skin health through various biological changes.

Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Nerves are crucial for the regeneration of various body parts in many animals.

Bioluminescence imaging can track hair follicle cells and help study hair regrowth.

FA2H is essential for normal fur and sebum production in mice.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

Only skin melanocytes, not other types, can color hair in mice.