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This study found that vitamin C deficiency in SMP-30/GNL-KO mice affected gene expression related to hair growth and cell growth, resulting in delayed hair growth compared to those with adequate vitamin C.

This study found that HPV8-induced actinic keratoses may mechanistically involve Lrig1+ hair follicle keratinocyte stem cells, with the E6 gene promoting downstream STAT3 activity in a mouse model.

This study reports the discovery of mutations in the PADI3, TGM3, and TCHH genes as molecular genetic causes of uncombable hair syndrome in children, indicating an autosomal-recessive inheritance pattern.

This study found that heterozygous mice overexpressing Claudin-6 experienced alterations in epidermal and hair follicle differentiation, leading to distinctive coat characteristics and a disrupted epidermal permeability barrier.

This study observed that chemically-induced intersex frogs displayed altered brain mRNA profiles, with finasteride increasing certain hormone-related gene expressions and fadrozole reducing aromatase activity without affecting gene transcript levels.

This study suggests an association between DNA methylation changes in hair follicles and inherited color dilution in Rex rabbits, contributing to a deeper understanding of epigenetic influences on rabbit pigmentation.

This study used whole-genome resequencing to analyze genetic diversity and selection in 17 rabbit breeds, identifying genes linked to traits like coat color and body size, which could inform breeding and conservation efforts.

This study identified putative causal mutations for PCOS among first-degree relatives, although functional analysis of a specific GDF9 mutation was unsuccessful.

This study found that eliminating senescent cells using senolytic drugs effectively prevented and reversed paclitaxel-induced peripheral neuropathy in mice.

This study found that BMP-2 activates Dlx3 gene transcription in murine keratinocytes by binding with Smad1/Smad4, suggesting a mechanism for BMP signaling's role in skin and hair follicle regulation.

This study identified key genes and miRNAs involved in feather morphogenesis in Zhedong White geese, highlighting a negative correlation between FOXO3 and miR-144-y.

This study investigated dermal fibroblasts in mouse skin using single-cell RNA sequencing and identified signaling pathways that influence adipogenesis, finding that IL-1-NF-κB promotes, while WNT-β-catenin inhibits, the adipogenic potential of these cells, with implications for wound healing and scar formation.

This study found that Runx3 deficiency in mice affects hair type and shape, suggesting it may regulate hair formation through interactions between dermal and epidermal layers.

This study found that proper levels of retinoic acid, controlled by the enzyme Cyp26b1, are essential for normal hair follicle development and morphogenesis in mice.

This study found that the orphan protein Plet-1 is expressed in specific keratinocytes of mouse hair follicles and may regulate keratinocyte interactions with inert tissues by affecting migration and adhesion.

In this study, researchers used mRNA sequencing to identify and categorize over 49,000 contigs in goat skin, revealing significant gene activity related to metabolism, cell cycle, and cell division during hair growth.

GNPTAB gene is crucial for normal hair color in humans and mice.

This study found that targeting IL-6, IL-1, and CCR6 signaling pathways may effectively reduce irradiation-induced alopecia and dermatitis in radiotherapy patients.

This study reported that the Undiagnosed Disease Program at Ghent University Hospital successfully provided definite diagnoses for 18% of referred adults with suspected rare diseases, primarily through genomic technologies.

In this study on mouse preputial glands, suppressing ATG7-dependent autophagy delayed age-related changes, affected lipid metabolism, and reduced pheromone production, highlighting autophagy's roles in glandular homeostasis and cell breakdown.

The researchers identified a pathogenic variant in the SRD5A2 gene among siblings with 46,XY disorder of sexual development, highlighting the importance of comprehensive genetic testing in diagnosis and management.

This study suggests that the curly hair phenotype in Mangalitza pigs may involve complex gene interactions related to calcium signaling and lipid metabolism, rather than changes in TRPM2 or CYP4F3 expression.

This study identified a 582-bp deletion upstream of LHX2 in cashmere goats, likely linked to hair follicle development and cashmere production, providing insights into genetic factors in cashmere trait selection.

This study found that ancient and modern Chinese goats share close genetic ties, originating from the Fertile Crescent, with genetic divergence influenced by China's climatic divisions.

This study found that hypospadias in male children is significantly associated with genetic polymorphisms in the Steroid 5 alpha reductase type 2 gene, higher parental age, consanguinity, rural residence, and preterm labor, with maternal age and rural residence being the strongest independent predictors.

In this study, Allium macrostemon Bunge extract was found to promote hair regrowth in a testosterone-induced androgenetic alopecia mouse model by activating Wnt/β-catenin signaling and boosting hair dermal papilla cell proliferation and growth factor expression.

This review examines the complexities of age-related skin healing and discusses how translating findings from model organisms to humans could enhance understanding and treatment of impaired regeneration in aging populations, but it reports no new clinical results.

In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.

This study identified enzymes responsible for regulating androgen action in the human prostate, suggesting that inhibiting AKR1C2 or RL-HSD may have therapeutic potential in androgen insufficiency or benign prostatic hyperplasia, respectively.

This review establishes a tolerable upper intake level of 255 μg/day for selenium in adults, warning that supplements and Brazil nuts may cause excess intake.