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Advanced human skin models improve drug development and could replace animal testing.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Cosmetics enhance beauty, fix defects, and intimidate enemies, with varying cultural standards and alternative methods.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

High levels of androgens during early development may cause PCOS-like symptoms.

Hoxc genes control hair growth through Wnt signaling.

Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.

Hair follicle regeneration possible, more research needed.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.