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PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Pannexin 3 is important for bone formation and the development of bone cells.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

South Asian women with PCOS present with different symptoms compared to White women, influenced by ethnicity, obesity, and age.

The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.

DNA methylation changes are linked to hair growth cycles in goats.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

PDI helps restore over-bleached hair's strength and structure by attaching special peptides.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.