research From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection
The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.
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research Chromatographic Methods for Determination of Finasteride and Tamsulosin Hydrochloride in Presence of Finasteride Degradation Product
Two methods can measure finasteride and tamsulosin hydrochloride; HPLC is more advantageous, while TLC offers better separation.
research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
research Frontotemporal Dementia with Parkinsonism Presenting as Posterior Cortical Atrophy
A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.
research Connexin 43 Expression in the Testes During Postnatal Development of Finasteride-Treated Male Rat Offspring
Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
research Hirsutism: From Brazil to a Place Near You
No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
research Current and Future Pharmacotherapy for Alopecia Areata
New treatments for hair loss show promise but need more research to confirm safety and effectiveness.
research Eosinophilia Associated with Clozapine – A Case Report
A patient's allergic reaction to clozapine resolved without stopping the medication, showing the importance of blood monitoring.
research Folliculitis Decalvans: A Multicenter Review of 82 Patients
Oral clindamycin and rifampicin are the most effective treatments for Folliculitis decalvans.
research Histopathological Characteristics May Not Be Useful in the Differential Diagnosis Between Basal Cell Carcinoma and Benign Tumors of Cutaneous Appendages Originating from Hair Follicle
Looking at tissue characteristics isn't reliable for telling apart basal cell carcinoma from certain benign skin tumors.
research Transcranial Photobiomodulation for Brain Diseases: Review of Animal and Human Studies Including Mechanisms and Emerging Trends
Light therapy on the brain shows promise for treating brain diseases and improving brain function.
research The Rho GTPase Exchange Factor Vav2 Promotes Extensive Age-Dependent Rewiring of the Hair Follicle Stem Cell Transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research Transcranial Focused Ultrasound-Mediated Unbinding of Phenytoin for Suppression of Chronic Temporal Lobe Epilepsy in a Rodent Model
Using focused ultrasound on the brain can help epilepsy medicine work better in rats.
research Beyond Counting Sheep: Exploring the Link Between Polycystic Ovary Syndrome and Sleep Health
PCOS often leads to sleep problems, especially obstructive sleep apnea, affecting overall health.
research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability
Early NAS level changes affect alcohol consumption vulnerability.
research Ultrastructural Characteristics of Neonate Scalp Hair
Neonate scalp hair is thinner, lacks a medulla, and has smaller follicles compared to adult hair.
research Lichen Planopilaris After Hair Transplantation
Oral minoxidil improved male baldness, but had side effects; certain antibiotics effectively treated a rare scalp condition; hair transplants might trigger another scalp condition.
research Study on the Cell Proliferation and Antioxidant Activity Effects of Different Extraction Methods of Salvia Miltiorrhiza Bunge and Scutellaria Baicalensis
Ethanol and ultrasonic wave extraction methods are best for making effective cosmetics and anti-hair loss products.
research Prevalence of Male and Female Pattern Hair Loss in Maryborough
Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.
research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders
Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
research Hair Follicles’ Transit-Amplifying Cells Govern Concurrent Dermal Adipocyte Production Through Sonic Hedgehog
Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
research New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence
The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
research Treatment of Vitiligo With the 308-nm Xenon Chloride Excimer Laser
The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.
research Feline Dermatophytosis: Contagion, Diagnosis, and Treatment
Combining systemic and topical treatments, guided by weekly fungal cultures, effectively treats cat ringworm.
research Psychodermatology: Emotional Factors and Treatment Approaches
The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.
research Tissue Resident and Follicular Treg Cell Differentiation Is Regulated by CRAC Channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Management of Adverse Events and Other Practical Considerations in Patients Receiving Capecitabine (Xeloda)
Capecitabine is as effective as intravenous treatments with fewer side effects, but requires careful management of Hand-foot syndrome and patient education.
research Minoxidil: Right Atrial Cardiac Pathology in Animals and Humans
Minoxidil may cause heart issues in animals and humans.