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This study found that WD-aptamer increased β-catenin expression and promoted human hair follicle dermal papilla cell proliferation by interfering with the CXXC5-Dvl1 interaction in the Wnt signaling pathway.

This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.

This study found that certain proteins linked to immune suppression and melanogenesis are associated with repigmentation in vitiligo patients undergoing standard treatment, suggesting these proteins and their pathways play roles distinct from merely reversing skin lesions.

This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.

This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.

This review suggests that although hydrolyzed collagen peptides with certain supplements may improve skin elasticity and joint function, evidence for collagen's anti-aging and regenerative benefits remains inconsistent.

This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.

Smart microneedles using advanced tech could improve psoriasis treatment.

This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.

This review highlights challenges in developing drugs targeting the Wnt/β-Catenin signaling pathway for cancer due to its complexity and essential roles in normal tissue. It explores targeted protein degradation technology as a promising strategy to overcome these challenges, suggesting potential new avenues for drug development.

This review discusses the potential of exosome therapy for treating diabetic peripheral neuropathy but highlights the need for more robust preclinical trials before clinical application.

This review examined the diverse therapeutic potentials of cannabinoids, highlighting their applications in pain, neurological, and cancer treatments, and emphasized the benefits of biodegradable polymers in improving drug delivery; however, further clinical trials are needed to fully explore these potentials.

This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.

This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

This review discusses the potential uses of inorganic nanomaterials for imaging and detecting brain diseases, but reports no new experimental results; it calls for improvements in diagnosis precision and imaging accuracy.

This review explores the potential of cell-mediated drug delivery systems in dermatology, highlighting their ability to target inflamed or diseased skin while discussing applications in diseases like atopic dermatitis and melanoma, along with challenges such as immunogenicity and manufacturing.

This study reports a unique case of trichotillomania as a presenting sign in a patient with neurological Wilson's disease, confirmed by genetic testing and copper abnormalities.

This study reports that hydrocolloid wound dressings emit energy capable of delaying evaporation in a potassium ferricyanide solution surrounding a hair follicle.

The researchers reported that adding specific combinations of hydrolyzed proteins to silicone-free shampoo improved hair conditioning properties by reducing friction and increasing surface adsorption and penetration into hair, compared to protein-free alternatives.

This study found that exposing seasonally anestrous mares to extended light periods led to the earlier onset of endocrinologically normal estrous cycles, potentially allowing earlier breeding and foaling.

This article discusses the causes and diagnosis of telogen effluvium, highlighting traction alopecia as a useful model for studying hair loss, but reports no new clinical results.

This case study describes a unique instance of warty dyskeratoma involving two adjacent hair follicles within one lesion.

This study suggests that controlling light exposure can influence cashmere growth by triggering hair follicles to enter their active growth phase sooner, potentially involving the CSDC2 gene as a key regulator.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

This research found that certain inflammasome proteins, like caspase-1, ASC, IL-18, and IL-1β, were elevated in patients with aneurysmal subarachnoid hemorrhage (aSAH) compared to controls and suggested these proteins could serve as reliable biomarkers for inflammation, potentially predicting worse outcomes.

This study demonstrated the usefulness of fully implantable loggers in measuring heart rate and sub-blubber temperature in captive harbour seals, with findings suggesting lower heart rates during molting and differences in temperature regulation between adults and sub-adults.

In this study, researchers reported that adult females approaching menopause in Canada generally had similar or lower blood concentrations of toxic, essential, and trace elements compared to their peers, but most participants showed zinc levels below the proposed adequacy threshold.

This study demonstrated that multipotential cells grafted onto matrices successfully grew new hair in 92% of mice, suggesting potential future applications in hair restoration using this method.

This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.