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The letters discussed medical tools, costs, treatment efficacy, and patient care complexities.

This perspective suggests that browning agents may not directly enhance UCP1 expression in white adipose tissue but instead induce browning through increased heat loss, prompting thermogenesis to compensate.

This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.

This review discusses gender-linked skin differences, such as hormone metabolism and sebum production, and reports no new findings; it suggests these insights might inform male-specific dermatological treatments or cosmetic products.

This review examines the role of hair follicles and sebaceous glands in percutaneous drug delivery but does not report new clinical results; it calls for further exploration of follicle-targeting therapies.

This review indicates that estrogen loss during menopause significantly impacts skin health, while estrogen treatment may increase skin collagen, thickness, and elasticity, though effects on other skin characteristics are inconsistent.

This review outlines the factors affecting skin greasiness and sebum production, highlighting measurement challenges but reports no new clinical findings; further research may guide sebosuppressive treatments for acne.

This study found that disrupting Adam10 in the epidermis led to severe skin and multi-organ abnormalities, implicating Adam10 as crucial for proper Notch signaling and skin maintenance.

This study found that feeding aged mice a probiotic yogurt induced changes leading to thicker, healthier fur, suggesting a bacteria-triggered interleukin-10-dependent mechanism that mimics signs of youth and reproductive fitness.

This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.

This article reviews the role of skin surface lipid in mediating environmental stressors and discusses potential therapeutic interventions, reporting no new experimental findings.

In this study, researchers found that human scalp hair, particularly when unwashed, can significantly react with ozone, reducing personal ozone exposure and increasing exposure to volatile reaction products.

This review explores how androgens and growth hormone influence the development of terminal hairs and sebaceous glands, attributing variability in hirsutism and acne to differing genetic sensitivities to androgens, but reports no new experimental data.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

In this study, researchers found that Asian hair contains more integral lipids than European or African hair, which may protect it better from UV-induced damage.

This guide reviews the biology of sebaceous glands and their evaluation methods, emphasizing their roles beyond lipid production in skin health and disease, and reports no new research results.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

In this study, lipid peroxides were found to induce apoptosis in hair follicle cells and advance the catagen phase in mice, suggesting a potential mechanism for alopecia development.

This study found that JunB, a transcription factor, is crucial for maintaining epidermal-pilosebaceous stem cell homeostasis by regulating progenitor cell behavior and preventing sebaceous gland dysfunction.

This review discusses the effects of oestrogen on skin ageing and highlights the need for large-scale clinical trials to evaluate postmenopausal oestrogen use, reporting no new findings.

This study reports that among men, skin surface hydration and pH change with age, but transepidermal water loss and sebum production show less variation.

This review discusses findings from genetic studies on acne, highlighting progress in understanding its molecular pathogenesis without reporting new clinical results.

This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.

This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.

This review summarized multiple molecular markers studied for their association with dry skin, finding considerable variability and uncertainty about which markers best indicate xerosis cutis.

This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.

This study found that age and follicular miniaturization were extremely weak predictors of total hair count in women with hair loss.

This study found that adiponectin significantly enhanced lipid production in human sebaceous glands and may be a potential target for treating conditions with reduced sebum production.

In this study, 13-cis-5S*,8S*-epidioxy-5,8-dihydroretinoic acid was found to be significantly more cytotoxic to cancer cell lines than other retinoic acid analogs evaluated.

This review discusses the critical parameters for MALDI IMS sample preparation in skin analysis and highlights its applications in wound healing, neoplasia, and infection research, but reports no new clinical results.