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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles may soon be used more for targeted and systemic drug delivery.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Probiotic bacteria improved skin and hair health in aged mice.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Shampoos are designed to clean and improve hair and scalp health, with specific ingredients for different hair types and conditions.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.

All three treatments reduce hirsutism, but spironolactone works best long-term.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

HIV can cause unusual and severe skin problems that are hard to treat.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

White hair grows thicker and faster than black hair due to higher activity of growth-related genes and proteins.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

Dermatologists need to know about cosmetics to help patients with skin issues and recommend safe products.