9 citations,
January 2017 in “Organic Process Research & Development” In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
9 citations,
January 2016 in “Skin Pharmacology and Physiology” The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
9 citations,
January 1999 in “Journal of Liquid Chromatography & Related Technologies” Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
8 citations,
January 2021 in “Pharmaceutics” Nanoporous silica entrapped lipid-drug complexes significantly improve the solubility and absorption of drugs that don't dissolve well in water.
8 citations,
March 2020 in “Metabolites” Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.
8 citations,
July 2018 in “Analytical sciences” Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.
8 citations,
May 2017 in “Chinese Journal of Integrative Medicine” Miscanthus sinensis flower extract may help promote hair growth and prevent hair loss.
8 citations,
January 2016 in “Annals of Dermatology” A complex of 5-aminolevulinic acid and glycyl-histidyl-lysine peptide may help increase hair count in male pattern hair loss without side effects.
8 citations,
April 2015 in “Advances in Psychosomatic Medicine” Psychotropic medications can cause skin problems but also treat some skin conditions.
8 citations,
July 2012 in “Cambridge University Press eBooks” Androgens can both increase body hair and cause scalp hair loss.
8 citations,
August 2011 in “Journal of Pharmacology and Experimental Therapeutics” Dosing time affects finasteride's effectiveness and safety in rats.
8 citations,
July 2011 in “Critical reviews in analytical chemistry” The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.
7 citations,
April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology” 11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
7 citations,
June 2017 in “Omics” The study developed a method to analyze ancient hair proteins using very small samples.
7 citations,
February 2014 in “Talanta” Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
7 citations,
June 2011 in “Movement Disorders” A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
6 citations,
April 2023 in “Frontiers in plant science” Certain bacteria can boost lentil growth and improve soil used for farming.
6 citations,
July 2021 in “The anatomical record” Different whale and dolphin species have unique whisker follicle structures, suggesting they might use their whiskers in various ways.
6 citations,
August 2020 in “Journal of Pharmaceutical Innovation” Nanoemulgel improves hair growth and quality using finasteride without irritation.
6 citations,
February 2020 in “Journal of Natural Products” A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.
6 citations,
October 2018 in “Endocrinology” Prenatally androgenized ewes can model increased hair diameter in women with PCOS.
6 citations,
March 2018 in “Journal of Chromatography A” New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.
6 citations,
January 2017 in “Dermato-endocrinology” ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.
6 citations,
February 2016 in “Journal of Microencapsulation” Improved finasteride formula allows slow, sustained release and better absorption for patients.
6 citations,
September 2014 in “Food Additives & Contaminants: Part A” New method effectively detects illegal hormones in anti-aging foods.
6 citations,
February 2014 in “Experimental Dermatology” Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
6 citations,
June 2011 in “British Journal of Dermatology” People with alopecia areata have higher levels of RBP4 protein and antibodies against it.
6 citations,
July 2009 in “Biomolecules & therapeutics” Combining MSM with MAP significantly promotes hair growth.
6 citations,
April 2004 in “Dermatologic Surgery” Finasteride showed limited hair growth and low patient compliance in treating male pattern baldness.
5 citations,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Rapamycin may help treat Leigh syndrome by targeting protein kinase C.