Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case report describes a 19-year-old patient with undiagnosed severe portopulmonary hypertension who experienced acute right ventricular failure and cardiac arrest following liver transplantation, subsequently managed with ECMO and a paracorporeal lung-assist device.

In a study using diabetic rats, researchers found that oral empagliflozin accelerated wound healing by reducing inflammation and oxidative stress, indicating potential benefits beyond blood sugar control for managing diabetic wounds.

This study highlights the severe health risks and dependence associated with non-medical androgen use among gym-goers, stressing the need for specialized primary care and harm-reduction strategies due to potentially fatal outcomes even after prolonged cessation.

This article highlights that early and high-dose corticosteroid therapy, along with immunosuppressive agents, is crucial for managing Vogt-Koyanagi-Harada disease, and emerging biological therapies may benefit refractory cases.

This review examines recent advances in bioelectronic nanogenerators for anti-cancer therapy, highlighting various transducing strategies such as photodynamic therapy and electrical stimulation, while also discussing the potential mechanisms for tissue repair and the challenges that lie ahead.

This review reports that chitosan-based systems with metal nanoparticles and polyphenols may enhance wound healing by improving the bioavailability and stability of these compounds, suggesting a potential new approach for chronic and diabetic wounds.

This narrative review highlights the potential of naturally occurring compounds to target specific molecular pathways and overcome resistance in advanced and recurrent papillary thyroid cancer, offering new therapeutic possibilities beyond traditional treatments like surgery and lifelong hormone replacement.

This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.

This review outlines that in women with PCOS, microRNAs (miRNAs) are abnormally expressed in various tissues compared to those without the condition, suggesting these miRNAs as potential biomarkers and therapeutic targets, given their role in pathways critical to PCOS and potential interactions affecting reproductive outcomes.

This review covers red light Transcranial LED therapy for hippocampal memory impairment in aging and Alzheimer's but reports no clinical results, highlighting a need for further research into its mechanisms and effects.

In this study, naringenin and its methylated derivatives reduced depression-like behaviors and inflammation markers in mice exposed to finasteride, suggesting their potential as effective and safe anti-depressive agents.

This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.

This review article connects key systemic lupus erythematosus pathobiology with current therapies, emphasizes clinical strategies for managing comorbidities, and stresses multidisciplinary care, but it reports no new clinical findings.

This review reports that Dang Gui (Radix Angelica sinensis) possesses bidirectional immunoregulatory effects, enhancing immune cell proliferation and function, and may benefit immune-related diseases such as cancer and anemia. It also evaluates regulatory and safety aspects, aiming to guide future research and clinical use.

This review discusses recent advances in polydopamine-based biomaterials and their growing potential in personalized medicine, but reports no new experimental results; the authors highlight both opportunities and challenges for future applications.

In this consensus statement, the Task Force of the Association of Cutaneous Surgeons of India found that over 90% of their experts agreed on the evidence strength, recommendation levels, and safety of six emerging dermatology treatments, providing guidelines for their clinical use.

This study found that living environment significantly influenced Fe concentrations in dog and cat hair, with outdoor animals showing higher levels than those kept indoors.

This study reported that NLRP3 plays complex roles in wound healing by initially promoting inflammation and delaying repair, but later enhancing structural restoration through distinct signaling pathways, highlighting its potential as a therapeutic target for controlling inflammation and regeneration phases.

This study found that acute stress can cause rapid hair loss by triggering necrosis in hair follicle cells and initiating autoimmunity, revealing a mechanism where stress-induced nerve activity leads to tissue damage and immune system activation.

In this study, researchers developed a polyphenol–amino acid nanozyme capable of controlled hydrogen peroxide delivery, which effectively activated hair follicles via oxidative stress in a mouse model, suggesting a potential non-pharmacological treatment for alopecia.

This study evaluated a levan-based polysaccharide, POLEVAN®, in shampoo formulations and reported that it significantly increased hair glossiness by 24%, allowed a reduction of surfactant content by up to 50% without affecting foam, and maintained scalp moisturization similar to hyaluronic acid in a clinical setting.

This research concludes that adipose mesenchymal stem cells are uniquely evolved to manage skin inflammation in newborns and their released molecules are the safest and most effective for skin therapeutics.

In a murine model of androgenetic alopecia, this study found that the newly designed IGF-1 biomimetic peptide Ac-GFFY-IGF led to faster and superior hair regrowth compared to minoxidil, suggesting potential for improved human therapies.

This study investigated the sub-acute toxicity of Eclipta alba extract in Wistar albino rats, finding generally comparable hematological and biochemical parameters to controls, but noted mild morphological liver and kidney changes at the highest dose, highlighting a key area for further safety research.

This study suggests that abnormal levels of zinc, copper, and iron in serum or hair may serve as auxiliary and prognostic tests for various skin diseases, though further research is necessary due to conflicting data.

This study found that sleep deprivation in mice can trigger prostatitis by activating the cGAS-STING pathway due to reduced levels of dihydrotestosterone and melatonin, resulting in a pro-inflammatory environment, while recovery sleep can mitigate these effects.

In this case report from People's College of Medical Sciences, a 20-year-old man initially misdiagnosed with Addison's disease was ultimately found to have strongyloidiasis, with his symptoms and weight loss improving after antihelminthic treatment.

This review of available data noted that oral minoxidil shows promise for treating various alopecia disorders, including androgenetic alopecia and alopecia areata, but high-quality studies are needed to better understand its effectiveness and mechanisms in these conditions.

This research observed that diabetes impairs wound healing in mice by disrupting key mechanotransduction pathways in fibroblasts, which are crucial for the healing process. The study also suggests transcriptomic changes could inform future diabetic wound repair therapies.

This review discusses the potential clinical benefits and functional properties of taurine as a conditionally essential amino acid, noting its presence in energy drinks, but reports no new experimental results.