March 2025 in “Journal of Medical Research and Surgery” This report details a case of severe protein-energy malnutrition resembling kwashiorkor in a 43-year-old woman after bariatric surgery, highlighting the crucial role of early diagnosis and a multidisciplinary approach in managing nutritional complications and improving outcomes in similar patients.
January 2025 in “Fitoterapia” This study reviewed literature on signaling pathways and concluded that these pathways are crucial pharmacological targets, influencing the mechanisms of drugs used in neurological, cardiovascular, and oncological treatments to correct signal transmission disturbances.
This study reports that in a rat model of myocardial infarction, Zn-Cu ion sequential therapy improved cardiac function and cardiomyocyte metabolic activity by precisely regulating ion concentrations and maintaining elevated levels of the Per2 protein, important for cellular repair.
This literature review reports that mesenchymal stem cell-derived secretome, including conditioned medium and extracellular vesicles, shows promise as an effective treatment for various diseases in animal and human in-vivo models, with ongoing clinical trials and recommendations for future research discussed.
May 2024 in “International journal of nanomedicine” This review highlights the potential of extracellular vesicles derived from medicinal plants as therapeutics for diseases such as cancer and inflammation, suggesting they may enhance the clinical use of herbal preparations, despite the challenges posed by extract complexity and individual variability.
April 2024 in “Proceedings” This study found a significant association between alopecia areata and low serum ferritin levels, suggesting that assessing and correcting iron stores might improve alopecia areata management.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study on adult-onset, whole body Spry1/2/4 triple knockout mice, researchers observed endocrine abnormalities and no increased tumor incidence, despite similar food intake and motor function.
This study in diabetic db/db mice found that treatment with the antihypertensive agents minoxidil or nebivolol stimulated elastogenesis and inhibited elastolysis, leading to restored elastic fibers, reduced aortic stiffening, and normalized blood pressure.
January 2024 in “Tropical journal of pharmaceutical research” This study found that extracts from Cirsium japonicum var. spinossimum seeds are rich in polyphenols and flavonoids, demonstrating significant anti-inflammatory and cell proliferation effects in specific cell models, suggesting potential as a source for anti-inflammatory and anticancer agents.
December 2023 in “Curēus” In this case study, a 36-year-old female with severe lupus enteritis and intestinal pseudo-obstruction showed significant clinical improvement after treatment with intravenous methylprednisolone, hydroxychloroquine, and cyclophosphamide, highlighting the complexities and challenges in diagnosing and managing atypical lupus manifestations.
January 2022 in “European Proceedings of Life Sciences” This article discusses the genetic polymorphisms affecting the antioxidant system and suggests that personalized detoxification plans and nutrition may be beneficial for patients with chronic diseases, but it reports no new clinical findings.
This article reviews knowledge-sharing efforts in pharmaceutical sciences at the University of Sorocaba, highlighting global collaboration on rational medicine use, without reporting new study results.
This article discusses the Graduate Program in Pharmaceutical Sciences at the University of Sorocaba and emphasizes collaborating internationally to improve health policies and practices but reports no new research findings.
May 2020 in “Fertility and Sterility” In this study, nonobese normotensive women with PCOS had higher left ventricular mass index compared to healthy controls, which was linked to inflammation and insulin resistance rather than androgen excess.
December 2019 in “University of Malaya Students Repository” This study found that Soxhlet extraction is more effective at removing the toxin mimosine from Leucaena leucocephala, and mimosine shows promise as a biodiesel additive due to its antioxidative properties.
This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.
This review explores the association between sleep disturbances, obstructive sleep apnoea, and metabolic consequences like Type 2 diabetes, but reports no new experimental results; the authors elaborate on existing knowledge and suggest complex interconnections with fat accumulation and various syndromes.
March 2017 in “Fundamental & Clinical Pharmacology” This case study reported an improvement in lower limb edema for a patient with type 2 diabetes mellitus after starting dulaglutide treatment, suggesting a potential role of the drug in sodium retention disorders.
January 2015 in “Indian Journal of Medical Biochemistry” Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
January 2015 in “Durham e-Theses (Durham University)” This study found that glucose starvation and hypoxia are physiological triggers of ER stress in in vitro differentiated adipocytes, rather than high concentrations of saturated fatty acids, cholesterol, or proinflammatory cytokines.
January 2009 in “Side effects of drugs annual” This chapter reviews drugs affecting blood coagulation and details the increased hemorrhage risk associated with warfarin interactions, liver disease, heart failure, and antiphospholipid antibodies but reports no new clinical results.
January 2009 in “Springer eBooks” The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
July 2026 in “Quality in Sport” This narrative review highlights that endurance, skill-oriented athletes, and physique-oriented competitors such as bodybuilders face accelerated degradation of fillers and botulinum neurotoxin due to elevated basal metabolic rates and other factors, and raised concerns about psychological conditions like body dysmorphic disorder in these populations.
This chapter reviews the challenges and future prospects of using nanotechnology and phytochemistry in developing safe, effective, and precision-based therapies for Polycystic Ovary Syndrome, without reporting new clinical findings.
July 2025 in “Scientific Reports” This study found that dermal papilla cell-conditioned medium can protect against UV-induced skin aging in a mouse model by modulating ferroptosis pathways, highlighting its potential for treating oxidative stress-related skin conditions.
January 2023 in “Book of Abstracts” COVID-19 can cause different types of hair loss, with telogen effluvium being the most common.
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July 2020 in “Applied Water Science” This study found high levels of toxic heavy metals in water sources of mining communities in Abakaliki, Nigeria, posing potential health risks including Parkinson's and Alzheimer's diseases.
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October 2011 in “Analytical biochemistry” This study used proteomic techniques to analyze human hair proteins, revealing keratin heterogeneity and identifying posttranslational modifications, such as cysteine trioxidation and methylation.
This study found that while iron depletion through phlebotomies is safe for women with functional ovarian hyperandrogenism, it does not improve their cardio-metabolic profile and may reduce non-enzymatic antioxidant capacity.
February 2021 in “Journal of pharmaceutical and biological sciences” This article reviews multiple treatments for alopecia areata, highlighting their variable efficacy and safety without any being curative; it reports no new clinical findings.