November 2021 in “International journal of life science and pharma research” This study reported that a solid lipid nanoparticle-based gel formulation, specifically optimized for psoriasis, improved drug loading capacity and release properties using high-pressure homogenization, suggesting its potential efficacy as a topical treatment.
40 citations
,
June 2013 in “Molecular Pharmaceutics” This study demonstrates that transfected epidermal stem cells using a novel 3D transfection system significantly enhanced wound healing and may serve as an effective therapeutic agent and gene delivery method for wound treatment.
39 citations
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August 2017 in “Colloids and Surfaces B: Biointerfaces” This study found that 50-nm PLGA nanoparticles delivered with iontophoresis enhanced skin permeation of indomethacin in rats more effectively than 100-nm nanoparticles, suggesting improved targeting of hair follicles.
32 citations
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June 2017 in “Journal of Pharmaceutical Sciences” This study found that coating liquid crystalline nanoparticles with chitosan significantly enhanced the skin permeation of 5α-reductase inhibitors, suggesting a promising strategy for improving topical delivery in androgenetic alopecia treatment.
21 citations
,
January 2023 in “Biomaterials Science” This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.
14 citations
,
February 2021 in “International Journal of Pharmaceutics” In this study, applying deer antler velvet extract-loaded niosomes and microspicules serum to the scalp significantly improved hair growth, melanin content, and skin hydration over 14 to 30 days without causing skin irritation.
8 citations
,
March 2018 in “Journal of Drug Delivery Science and Technology” This study found that treating paracoccidioidomycosis-infected mice with a nanoparticle formulation of itraconazole led to higher drug accumulation in lung, liver, and spleen tissues, improved treatment efficacy, and reduced side effects compared to traditional oral solutions.
6 citations
,
December 2015 in “International journal of nanomedicine” This study found that low-frequency sonophoresis significantly decreased the skin penetration of sodium fluorescein-loaded PEGylated liposomes with D-limonene and affected percutaneous absorption by partially plugging hair follicle orifices.
26 citations
,
March 2014 in “International journal of pharmaceutics” This study confirmed that the novel solid lipid microparticle formulation of adapalene demonstrated follicular penetration potential and targeted particle erosion in sebum in in vitro tests.
5 citations
,
August 2020 in “Stem Cell Research & Therapy” This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.
May 2022 in “International Journal of Clinical Trials” This study concluded that platelet rich fibrin (PRF) may enhance healing and functional recovery compared to platelet rich plasma (PRP) during immediate post-extractive dental implant procedures.
December 2023 in “Azerbaijan Pharmaceutical and Pharmacotherapy J” This study formulated a minoxidil-loaded submicron emulsion-based topical gel, which demonstrated effective in vitro release, ex vivo permeation, and stability, suggesting it may offer a targeted treatment approach for alopecia compared to traditional methods.
May 2018 in “Dermatologic Surgery” This overview describes the Dermatologic Surgery journal's extensive coverage of cosmetic and reconstructive skin surgery, but it reports no new research findings.
January 2023 in “The Egyptian Journal of Hospital Medicine” This study found that topical valproic acid and 5% minoxidil both significantly increased hair count in patients with female pattern hair loss, suggesting topical valproic acid as a potential treatment option.
November 2014 in “John Wiley & Sons, Ltd eBooks” This review discusses hormones that affect acne and highlights a statistically significant link between a low-glycemic-load diet and reduced acne activity, but reports no new experimental findings.
2 citations
,
November 2024 in “Wildlife Society Bulletin” The researchers found that combining permethrin (44%) and fluralaner effectively reduced tick load in moose calves, as indicated by less severe hair loss, compared to untreated calves, while topical permethrin (5%) alone had no clear effect on tick load, body mass, or hematocrit.
49 citations
,
August 2007 in “Dermatologic surgery” This review discusses newer therapeutic techniques for treating postacne scarring, highlighting their effectiveness for particular grades of scars, and reports no new clinical results.
45 citations
,
January 2021 in “Drug Delivery” In this study, researchers developed a biomimetic anti-inflammatory nanosystem (MM-CEP/NLCs) that significantly reduced the severity of acute lung injury in vivo by targeting and accumulating in lung inflammation sites, showcasing its potential for treating inflammation.
43 citations
,
March 2017 in “Drug Design Development and Therapy” The researchers reported that a new nanoformulation of paclitaxel-loaded nanoparticles showed superior antitumor effects against malignant melanoma in vitro and in vivo compared to the commercial formulation Taxol®.
34 citations
,
October 1982 in “Journal of applied polymer science” This study found that the moisture content of human hair significantly influences the type of fracture under tensile loading, with low or high humidity levels leading to smooth fractures and intermediate humidity resulting in step fractures.
24 citations
,
September 2020 in “Pharmaceutics” In this study, solid lipid microparticles loaded with lidocaine hydrochloride were developed to effectively deliver pain relief and antimicrobial benefits for wound management, demonstrated by testing with bioengineered skin substitutes and showing effectiveness against common wound-infecting bacteria.
21 citations
,
April 2021 in “ACS omega” In this study, curcumin was efficiently loaded into PS–PAA nanoparticles at the formation stage, showing even distribution at low concentrations and good biocompatibility with human skin fibroblasts.
13 citations
,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
8 citations
,
March 2020 in “Dermatologic Therapy” This study found that a new formulation kit of Pielus Anti-hair loss lotion and shampoo, used daily for 90 days, was safe and effective in reducing hair loss and increasing hair strength and density among patients with telogen effluvium and/or androgenetic alopecia.
5 citations
,
May 2023 in “Frontiers in Immunology” This review provides an overview of how advancing imaging technologies, such as tissue clearing and intravital microscopy, are enhancing our understanding of tumor architecture and interactions between cancer cells and the tumor microenvironment, aiding both fundamental cancer research and the development of therapies.
4 citations
,
July 2025 in “International Journal of Nanomedicine” This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.
4 citations
,
December 2024 in “International Journal of Nanomedicine” This study found that PPD-Lip@RES may effectively promote hair growth in models of telogen effluvium and androgenetic alopecia, suggesting its potential as a promising treatment strategy by addressing the underlying pathological and physiological processes of hair loss.
2 citations
,
December 2021 in “Pharmaceutics” This study demonstrated that a finasteride-loaded proniosome significantly enhanced transfollicular delivery and hair growth in mice without causing skin irritation, with effects comparable to a 2% minoxidil solution.
1 citations
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March 2019 in “International Journal of Cosmetic Science” In this study, researchers developed a regression model that reasonably predicts consumer-perceived hair breakage using various parameters such as hair smoothness, detangling forces, extensional strength, and hair density among Indian women.
January 2025 in “RSC Advances” This study reported that a new formulation of finasteride solid lipid nanoparticles, combined with LPC and NTC, enhanced hair growth in mice without visible skin reactions, suggesting it could effectively manage androgenetic alopecia.