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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

A woman's hair loss was caused by her husband's testosterone gel and a diabetic man's nail disease led to bone infection, both treated successfully.

Ayurvedic treatment improved symptoms and reduced TSH levels in a hypothyroidism patient.

Losing weight, possibly through bariatric surgery, is key to improving PCOS and hyperandrogenism symptoms in obese patients.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

The document concludes that various hair disorders have different treatments, including medication, surgery, and addressing underlying causes.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Darker skin in 10-year-old girls may be an early sign of puberty.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

A pregnant woman with Werner's syndrome died during childbirth, but her baby survived and did not have the syndrome.

The letter argues that blaming synthetic hair implants for scalp cancer based on one report is biased and possibly coincidental.

A postmenopausal woman's facial redness, acne, and excess hair were caused by too much hormone therapy for insomnia, but improved after stopping the treatment.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

A postmenopausal woman's excessive hair growth and hair loss were due to a non-cancerous ovarian condition, treated successfully with surgery.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Men with frontal male pattern baldness may have a higher risk of gastric cancer.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Hormonal implants have many side effects that often outweigh their benefits.

Surgical removal of a rare ovarian tumor improved symptoms and hormone levels in a postmenopausal woman.

Hirsutism in young girls can have various causes beyond PCOS, so diagnoses should be reconsidered if treatments don't work.

The case highlights the complexity of diagnosing high testosterone in older women and the need for thorough testing.

Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.