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Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.

Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.

Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.

Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.

Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.

The Trichoscan system was found to be inaccurate for measuring hair growth, needing better software to be useful.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Claudin-1 is important for the barrier function and growth of hair.

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Hair loss requires customized treatments based on its various causes and types.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

A different gene near the hairless gene on chromosome 8p21 causes a rare hair loss condition in a German family.

Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

The conclusion is that exogen is a unique hair cycle phase and the new sampling method specifically targets this stage, which may help in future hair loss research.

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.

The study concluded that scalp tumors show different patterns based on age, gender, and tumor thickness, and emphasized the importance of early detection and scalp examinations.