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Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Humans lost body hair relatively recently in evolution.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Probiotic bacteria improved skin and hair health in aged mice.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Liposomes could improve how skin care products work but are costly and not very stable.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.