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The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

ΔNp63α helps control a protein that stops cancer cells from spreading.

Systemic diseases can cause hair loss, which is often reversible with treatment.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Higher DHT in male baldness may protect against prostate cancer.

Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.

The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Dietary supplements might help prevent post-COVID hair loss, but serum ferritin is not a reliable indicator.

Different treatments for PCOS should be tailored to the individual, including lifestyle changes and various medications.

Hashimoto thyroiditis is an autoimmune disease that can lead to an underactive thyroid and is treated with medication and sometimes diet changes or surgery.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Up to half of people experience itchy scalp, often due to skin conditions like seborrheic dermatitis or psoriasis, and treatments vary based on the specific cause.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

The document suggests more research is needed to understand the link between baldness and prostate cancer.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

Lupus can be a rare cause of high calcium levels in the blood.

The skin produces and processes hormones, affecting both local and overall body functions.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

An 11-year-old boy in Saudi Arabia has a rare case of hypoparathyroidism with severe brain calcifications but normal development and no known cause.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

VDR regulation varies by tissue and is crucial for its biological functions.

Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.

A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.

Further research is needed to understand how the microbiome affects hair loss in Alopecia Areata.

Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.

Obesity and bariatric surgery can cause hair thinning and temporary hair loss due to nutritional deficiencies and stress.