7 citations
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January 2022 in “Plants” This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.
5 citations
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February 2020 in “European Food Research and Technology” This study provides a detailed profile of bioactive polyphenols in various parts of the baobab fruit, highlighting its potential as a health-promoting food or supplement.
4 citations
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November 2022 in “Acta dermato-venereologica” This study found that patients with hidradenitis suppurativa had lower trabecular bone score and total hip bone mineral density compared to controls, with a high prevalence of vitamin D deficiency.
1 citations
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January 2018 in “Journal of clinical & experimental dermatology research” In this study, researchers found no significant difference in vitamin D levels between psoriasis patients and controls, suggesting no association between vitamin D deficiency and psoriasis.
December 2025 in “Frontiers in Nutrition” This review suggests that although hydrolyzed collagen peptides with certain supplements may improve skin elasticity and joint function, evidence for collagen's anti-aging and regenerative benefits remains inconsistent.
January 2025 in “Ginekologia Polska” In this study, researchers found that certain vitamin D receptor gene polymorphisms are significantly related to insulin concentration during a glucose tolerance test in young women with hyperandrogenism, but these polymorphisms did not affect bone metabolism or other biochemical parameters.
December 2020 in “Our Dermatology Online” This study found that there was a significant discrepancy between histopathological examination and clinical diagnosis in alopecia cases, while vitamin D levels were not significantly associated with alopecia.
January 2020 in “Publications of the UdS (Saarland University)” This meta-analysis found an association between lower vitamin D levels and increased risk of Alopecia areata, though causation cannot be established due to the study designs.
In this study, female patients with Female Pattern Hair Loss were found to have significantly lower serum levels of vitamin D and ferritin, as well as lower total cholesterol and triglyceride levels, compared to healthy controls, suggesting these factors may contribute to the condition's pathogenesis.
October 2021 in “Journal of Advanced Biomedical and Pharmaceutical Sciences” This study reviews polycystic ovary syndrome and vitamin D, reporting no new results, and notes the involvement of vitamin D receptors and insulin in ovarian function.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the mutant hairless rhino bald protein in mice interacts with the vitamin D receptor but cannot repress its transactivation and shows abnormal cellular localization.
January 2008 in “HAL (Le Centre pour la Communication Scientifique Directe)” This study identified complex regulatory elements and interactions involving the Hr gene and HR protein that are crucial for hair follicle formation and cycling in mammals.
215 citations
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September 2003 in “Journal of Biological Chemistry” This study found that the hairless gene product (Hr) suppresses VDR-mediated gene activation by directly interacting with the vitamin D receptor, potentially affecting hair follicle function.
144 citations
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December 2004 in “Molecular Endocrinology” This study found that the effects of the vitamin D receptor on hair follicle cycling in mice are independent of its ability to bind a hormone, with specific domain mutations influencing hair regrowth outcomes.
140 citations
,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that mice lacking the 1αOHase enzyme, which is responsible for producing a key vitamin D metabolite, showed impaired epidermal differentiation and delayed recovery of skin barrier function after disruption.
119 citations
,
January 2012 in “Nutrition & Metabolism” This article suggests that modern lifestyle changes, including diet, stress, and chronic anti-inflammatory medication use, may disrupt the natural process of inflammation resolution, increasing vulnerability to chronic disease.
109 citations
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June 2011 in “Molecular and Cellular Endocrinology” Vitamin D receptor mutations can cause alopecia by affecting hair growth genes.
55 citations
,
January 2000 in “Cell biochemistry and function” This study observed that patients with alopecia had increased lipid peroxidation and decreased antioxidants, including lower beta-carotene, GSH levels, and GSH-Px activity, compared to healthy controls.
50 citations
,
October 1986 in “European journal of pediatrics” This case study reported that absence of alopecia does not reliably predict responsiveness to vitamin D treatment in Vitamin D-dependent rickets type II, as demonstrated by a patient with normal hair growth who showed extreme resistance.
24 citations
,
November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” In this study, mutations in the vitamin D receptor were identified in Brazilian children with rickets and alopecia, leading to impaired receptor activation and reduced 24-hydroxylase expression.
24 citations
,
August 2009 in “Expert opinion on pharmacotherapy” This article highlights the benefits of combining calcipotriene and betamethasone for treating localized plaque-type, scalp, and nail psoriasis, enhancing effectiveness while reducing side effects compared to single-agent therapies.
23 citations
,
January 2017 in “Journal of Oleo Science” This review discusses the use of supercritical carbon dioxide for extracting rice bran oil, noting its advantages over conventional methods for preserving nutrients and antioxidants, but provides no new experimental results.
20 citations
,
February 1977 in “The anatomical record” This study found that excess vitamin A in organ cultures of mouse embryos led to significant changes in epidermis and hair follicles, altering morphogenesis and polysaccharide distribution.
18 citations
,
July 2010 in “Expert Review of Endocrinology & Metabolism” This study identified an association between the FTO gene and susceptibility to PCOS, providing the first genetic evidence linking PCOS to obesity.
18 citations
,
September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.
16 citations
,
December 1996 in “International Journal of Dermatology” This case report describes a 23-year-old man with scurvy, characterized by perifollicular hemorrhages, gum disease, and other symptoms due to a diet low in fresh fruits and vegetables.
15 citations
,
May 2017 in “Journal of Cellular Biochemistry” This review discusses the role of the hairless protein (HR) in alopecia and cancer, noting its potential importance in cancer cell growth and survival, and reports no new experimental results.
13 citations
,
September 2007 in “International Journal of Dermatology” This study suggests no significant association between vitamin D receptor gene polymorphisms and alopecia areata.
12 citations
,
October 2021 in “Journal of the Science of Food and Agriculture” This study found that adding vitamin A to the diet improved hair follicle density and fur quality in heat-stressed Rex rabbits, involving specific signaling pathways.
11 citations
,
July 2021 in “Nanomaterials” This study found that α-13′-carboxychromanol significantly accelerated wound healing and improved tissue quality in a mouse model, especially when delivered with bacterial nanocellulose under diabetic conditions.