13 citations
,
May 2012 in “Cutaneous and ocular toxicology” In this study, researchers found no significant differences in vitamin B12, folate, and homocysteine metabolism between patients with alopecia areata and controls, suggesting no association with vitamin B12 deficiency.
13 citations
,
September 2007 in “International Journal of Dermatology” This study suggests no significant association between vitamin D receptor gene polymorphisms and alopecia areata.
13 citations
,
April 1994 in “Baillière's clinical endocrinology and metabolism” This review discusses inherited forms of vitamin D-dependent rickets and explains their genetic and metabolic causes but reports no new clinical findings.
12 citations
,
September 2017 in “JDR Clinical & Translational Research” In this study, researchers observed that the success of treating hereditary vitamin D–resistant rickets in children depends on the mutation location in the VDR gene, notably with favorable dental development outcomes for those with the p.R391S mutation, despite persistent alopecia.
12 citations
,
January 2016 in “Journal of Clinical and Investigative Dermatology” This study examines how the Severity of Alopecia Tool score was used to assess Alopecia Areata in patients while excluding systemic conditions that might affect vitamin D levels, but reports no new clinical results.
12 citations
,
October 1952 in “Experimental biology and medicine” This study found that in young male rats, cortisone acetate inhibited body growth and caused alopecia, which vitamin B12 and aureomycin largely counteracted, especially when combined.
12 citations
,
October 2021 in “Journal of the Science of Food and Agriculture” This study found that adding vitamin A to the diet improved hair follicle density and fur quality in heat-stressed Rex rabbits, involving specific signaling pathways.
12 citations
,
September 2020 in “Nanomaterials” This study found that centrifugally spun scaffolds with higher concentrations of platelet-derived bioactive molecules enhanced melanocyte metabolic activity and proliferation, suggesting potential for improving vitiligo treatment.
12 citations
,
December 2016 in “The FASEB Journal” This study found that the absence of vitamin D receptor-mediated suppression of PPARγ expression causes hair loss in VDR-null mice.
12 citations
,
September 2014 in “Bone” This study characterized two siblings with hereditary vitamin D resistant rickets and a mutation in the vitamin D receptor, finding no immune-related disorders despite a defective T cell response to vitamin D.
12 citations
,
October 2013 in “British Journal of Dermatology” This meeting report provides an overview of recent evidence on vitiligo treatments, indicating a lack of standardized outcome measures and emphasizing the need for more consistent clinical trials.
12 citations
,
September 1997 in “PubMed” This review explores how vitamin D3 analogs could target various skin processes and diseases, potentially offering selective and effective treatments beyond psoriasis, but reports no new clinical findings.
11 citations
,
June 2012 in “Archives of Dermatological Research” This study demonstrated that high doses of L-cystine and vitamin B6 effectively prevent doxorubicin-induced hair loss in mice.
11 citations
,
January 2011 in “Turkish Journal of Medical Sciences” This study found that iron deficiency anemia is a key factor in the development of telogen effluvium, and higher 25-hydroxyvitamin D3 levels in TE patients may be linked to increased UV exposure.
11 citations
,
August 1987 in “Archives of Dermatology” In this study, researchers found that Langerhans' cells likely do not play a role in the depigmentation process in C57Bl/Ler-vit.vit mice, as their number was normal during depigmentation and highest afterward.
11 citations
,
September 2024 in “Journal of the European Academy of Dermatology and Venereology” This review explores the shared pathogenesis of alopecia areata and vitiligo and compares treatment responses, noting that hair regrowth in alopecia areata occurs more rapidly than skin re-pigmentation in vitiligo, possibly due to differences in stem cell biology and treatment effects on melanocytes.
11 citations
,
November 2021 in “JBMR plus” This review discusses the role of the unliganded vitamin D receptor in hair follicle cycling and tumor formation in mice and reports no new experimental findings.
11 citations
,
May 2021 in “Clinical Epidemiology” This study found that the prevalence of vitiligo in Germany is higher in clinical exams than in claims data, suggesting many patients may not seek medical help due to unsatisfactory treatment options.
11 citations
,
January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This case report observed that while a 4-year-old boy with vitamin D-dependent rickets type II showed biochemical and bone improvement after vitamin D and calcium treatment, his alopecia did not improve.
11 citations
,
March 2015 in “Life sciences” This study found that using conditioned medium from vitamin D3 pre-activated preadipocytes enhanced hair regeneration in mice by promoting angiogenesis.
11 citations
,
July 2014 in “American Journal of Clinical Dermatology” This study observed higher rates of H. pylori infection in vitiligo patients compared to those with telogen effluvium, though no significant association was found with vitiligo disease activity or pattern.
11 citations
,
January 2011 in “Journal of Cutaneous and Aesthetic Surgery” This study on a 30-year-old male reported that single-hair follicular unit transplant effectively repigmented a stable vitiligo patch, achieving complete pigmentation in 8 weeks with no recurrence after 6 months.
11 citations
,
June 1996 in “Nutrition” Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.
11 citations
,
August 1986 in “Archives of Dermatology” This case report describes a patient with skin and nail hyperpigmentation and premature gray hair due to vitamin B12 deficiency, which were reversed after treatment with cyanocobalamin.
10 citations
,
January 2017 in “Skin Pharmacology and Physiology” This case report describes a 52-year-old man who developed generalized vitiligo two months after stopping finasteride and suggests this may be part of post-finasteride syndrome.
10 citations
,
July 2022 in “Journal of the Turkish-German Gynecological Association” In this study, micronutrient intake was associated with androgen levels in women with PCOS, with the association more pronounced in NA PCOS compared to HA PCOS groups.
10 citations
,
January 2019 in “Advances in Clinical and Experimental Medicine” This meta-analysis reported a significant association between vitamin D receptor gene ApaI polymorphism and polycystic ovary syndrome risk, with variations observed between Asian and Caucasian populations.
10 citations
,
August 2016 in “Oxford Medical Case Reports” This case report describes the development of halo naevi, vitiligo, and diffuse alopecia areata in a 33-year-old woman undergoing tocilizumab therapy, suggesting a link between these conditions and cellular and humoral immune factors.
10 citations
,
June 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that the vitamin D receptor plays a crucial role in promoting differentiation and protecting against UVB-induced DNA damage in murine melanocytes, suggesting potential implications for melanoma progression.
10 citations
,
September 2015 in “PLoS ONE” This case report documents a female toddler with novel compound heterozygous mutations in the VDR gene causing hereditary 1,25-dihydroxyvitamin D-resistant rickets, expanding the known mutation spectrum for this disease.