195 citations
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January 2008 in “Photochemistry and Photobiology” This review discusses the effects of visible light on human skin, highlighting its role in pigmentation, thermal damage, and the treatment of several skin conditions, while noting limited sunscreen protection against it; no new clinical results are reported.
35 citations
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December 2014 in “Lasers in surgery and medicine” This study found that red light accelerated the transition from the resting to growth phase in hair follicles faster than green and blue light in mice, suggesting it may stimulate hair growth.
9 citations
,
January 2018 in “Medical research archives” This review discusses the therapeutic use of photobiomodulation for various skin conditions, highlighting its efficacy in accelerating tissue repair, reducing inflammation, and treating pigmentary disorders and other skin diseases, but it reports no new clinical results.
7 citations
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September 2004 in “International Journal of Cosmetic Science” This study demonstrated that visible light lightens blond hair more effectively than ultraviolet light, attacking melanin granules directly, whereas ultraviolet light primarily damages other hair tissues following washing.
4 citations
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June 2022 in “Journal of cleaner production” This study found that a new eco-friendly hair crosslinking method using visible light and non-toxic chemicals caused less damage and improved mechanical properties compared to traditional thioglycolic acid treatment.
3 citations
,
June 2023 in “ACS sustainable chemistry & engineering” In this study, a method using riboflavin phosphate, citric acid, and polyols successfully optimized protein cross-linking in hair of all colors through visible light-mediated photo-cross-linking, improving the mechanical properties and hair-setting effects without the influence of hair color.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that while 450nm blue light can inhibit collagen and induce oxidative stress in dermal fibroblasts, 850nm near-infrared light may enhance metabolic activity without causing oxidative damage, suggesting potential for tailored light therapies in skin treatments.
117 citations
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September 2013 in “Lasers in Surgery and Medicine” This study found that low level laser therapy at 655 nm significantly increased hair counts in males with androgenetic alopecia.
17 citations
,
December 2015 in “International Journal of Cosmetic Science” This review discusses the effectiveness of non-thermal, non-ablative devices like light-emitting diodes in treating various skin and hair conditions but reports no new clinical findings.
2 citations
,
March 2025 in “Archives of Dermatological Research” HEV light can harm or help skin and scalp, so safe exposure guidelines are needed.
27 citations
,
January 2018 in “Drug Delivery” In this study, researchers investigated a new local drug delivery system using glycol chitosan hydrogel and doxorubicin (GC10/DOX) for thyroid cancer in mice, finding it produced a stronger antitumor effect compared to conventional treatment methods.
81 citations
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August 2014 in “Lasers in Surgery and Medicine” This study found that low-level laser therapy significantly increased hair growth in women with androgenic alopecia, achieving a 37% greater increase in hair counts compared to placebo.
22 citations
,
July 2004 in “International Journal of Cosmetic Science” This article reviews the impact of UV radiation and visible light on human hair structure and summarizes protective strategies, reporting no new clinical results.
144 citations
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December 2017 in “Pigment cell & melanoma research” This review suggests that melasma may be a photoaging skin disorder affecting genetically predisposed individuals, which could significantly influence its treatment and prevention strategies.
86 citations
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June 2017 in “Anais Brasileiros de Dermatologia” This review discusses the role of antioxidants in managing oxidative skin damage and reports no new results, emphasizing the need for understanding their mechanisms, limitations, and risks for safe use.
24 citations
,
January 2009 in “International Journal of Trichology” This review discusses the mechanisms by which sunlight exposure aggravates hair aging and highlights the role of hair pigments in providing photochemical protection, reporting no new results.
18 citations
,
March 2009 in “Skin pharmacology and physiology” This study found that sunlight exposure causes significant structural and chemical damage to hair, including cuticle loss, cortex damage, and discoloration, with water playing a major role in discoloration of brown hair.
2 citations
,
November 2018 in “International Journal of Cosmetic Science” This study proposes a simple fluorescence method to evaluate hair damage and protection, suggesting that emissive properties of hair can aid in substantiating cosmetic claims.
May 2026 in “Journal of Photochemistry and Photobiology” This review found that solar radiation, pollution, and trace metals cause significant damage to human hair, with factors like UVB radiation primarily affecting light-colored and bleached hair; most data were derived from in vitro and ex vivo simulations.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” In this study, researchers suggest that digital microscopy using visible light could offer a more objective approach to diagnosing hirsutism by quantifying terminal hair, with future research needed to assess its usefulness in women with the condition.
November 2022 in “Journal of Investigative Dermatology” This study found that in mouse melanocytes, the cytoplasmic dynein complex component Dynlt3 is necessary for proper melanosome transport, acidity regulation, and effective transfer to keratinocytes, linking it to skin pigmentation processes.
September 2024 in “Pakistan Journal of Science” This systematic review suggests that laser treatments, especially low-level laser therapy and excimer lasers, may be effective for hair regrowth, though further large-scale studies are needed for validation.
This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.
303 citations
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August 1971 in “The American Journal of Medicine” This report suggests that in vitiligo, melanocytes may be destroyed by the same factors necessary for melanin production, contributing to the skin's depigmentation.
4 citations
,
August 2016 in “PubMed” This study analyzed how oxidative hair dye leaches from pigmented and nonpigmented hair during wash cycles, finding that melanin influences the dye deposition and leaching processes.
7 citations
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January 2003 in “Journal of cosmetic and laser therapy” This study concluded that the Spa Touch system effectively retards hair regrowth, functioning like a "light razor" for quick and cost-effective epilation.
April 2025 in “Journal of Applied Cosmetology” This study found that a combination of microneedling with growth factors and low-level light therapy led to visible hair regrowth without side effects in a patient with trichotillomania.
4 citations
,
May 2021 in “Lasers in Surgery and Medicine” This study observed that adding low-level light therapy with the GentleWaves® device to Minoxidil significantly boosted hair regrowth in men with androgenetic alopecia by reducing scalp inflammation.
13 citations
,
January 2001 in “Pediatric dermatology” This study reports pseudopili annulati in a dark-haired Chinese girl, identifying the unique appearance and structural characteristics of her hair without finding abnormalities in the cuticle and cortex.
This study introduces a novel visible light-mediated intramolecular [2+2] cycloaddition process that forms 6-azabicyclo[3.1.1]heptanes, offering a new synthesis route for bioisosteric mimetics used in drug discovery, potentially expanding medicinal chemistry applications beyond traditional limitations.