Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study demonstrates that pH-responsive nanogels designed with comb-like anionic polymers significantly improved oral delivery of the chemotherapy drug camptothecin, enhancing drug stability in acidic conditions and release in the intestines, with increased cellular uptake and cytotoxic effects against colorectal carcinoma cells.

This study found that modern styling cosmetics can significantly alter hair structure through changes in interfacial chemistry and cohesion, particularly when applied to already damaged hair.

In a study using female Wistar rats, the researchers found that a liquid allantoin-enriched pectin hydrogel significantly improved wound healing, achieving a 71.43% reduction in healing time and complete wound closure in 15 days.

This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.

This study found that spanlastic gel loaded with thymoquinone and ascorbic acid improved skin deposition and tyrosinase inhibition, suggesting potential as a treatment for hyperpigmentation.

In this study, researchers developed an environmentally friendly hair coating from casein proteins and tannic acid, enhancing the tensile strength of virgin Asian hair by approximately 21% compared to untreated hair, while maintaining elasticity.

This study explored Black Sea shark liver oil-based emulgels, finding that the addition of borage oil (Gel 2) enhanced the anti-inflammatory and wound healing properties compared to shark liver oil alone (Gel 1) and a reference diclofenac gel, suggesting promising eco-friendly applications in dermatocosmetics.

This review discusses the role of fascial mobilization in wound healing and its potential implications for treating chronic skin wounds and scarring, but reports no new clinical results.

This research found that hyaluronic acid increased cell proliferation and type I collagen more effectively than poly-L-lactic acid in both human fibroblast cultures and rat dermis.

This study developed granular hydrogels with reversible interparticle cross-linking, finding they offer high mechanical stability and enhance cell recruitment, making them promising for injectable and 3D printable scaffolds in tissue engineering and therapeutic delivery.

This review discusses the potential applications and advantages of encapsulating single cells for use in therapeutics and diagnostics, while also evaluating various methods for effectively creating and sorting single-cell units despite challenges in production and cost.

This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.

This study found that Cupiennius salei spiders have specialized mechanosensitive hairs on their legs that adaptively respond to joint movements during walking, suggesting a proprioceptive function.

This review highlights recent advancements in using nanotechnology for scar prevention and treatment, emphasizing the unique properties of nanomaterials in drug delivery and the challenges that remain in maximizing their potential for effective scar interventions.

This study investigated a gelatin-based bioink for 3D bioprinting a simplified skin model, finding that a formulation with 15% gelatin and 150 mM calcium chloride supported a homogeneous distribution of viable cells over 14 days, showing promise for drug evaluation applications.

This review introduces a framework to integrate bioinspired conductive materials and advanced 3D/4D printing in regenerative medicine for dynamic, responsive tissue regeneration, emphasizing the potential of smart scaffolds to adapt to physiological cues.

This review discusses the roles and mechanisms of glycosaminoglycans in wound healing and presents challenges and potential applications for GAG-based biomaterials without reporting new experimental results.

This review examines advancements in hydrogel formulations aimed at preventing dermal fibrosis and promoting scarless wound healing, highlighting their role in regulating myofibroblast differentiation and controlling the wound microenvironment.

In this study, a copolymer made from Tung oil and Tung free fatty acids demonstrated improved mechanical and thermal properties for hair repair, with enhanced resistance and flexibility observed in treated bleached hair, suggesting its potential as a sustainable biopolymer for cosmetic applications.

This narrative review synthesizes findings suggesting that exosomes show promise for dermatological and regenerative applications, with early human studies indicating acceptable safety and potential benefits for wound care, rejuvenation, and alopecia, though clinical and regulatory development is still in its infancy.

This study developed a biodegradable nonwoven textile using a starch-based biopolymer and fruit extracts, resulting in materials that are stronger, more hydrophilic, and capable of releasing beneficial compounds over 72 hours, positioning them for potential use in medical, healthcare, and cosmetic applications.

In this study, researchers reported that hair follicle stem cells maintain quiescence through a PIEZO1-dependent mechanism that senses mechanical forces and translates them into localized calcium influx, involving a transcriptional network that regulates cell adhesion and cytoskeleton-related genes.

This study aimed to enhance the skin penetration of brown algae fucoidan using a Nanostructured Lipid Carrier, achieving a formulation with good physical quality and stability.

This study found that alkylation of kerateine cysteine residues created a cell-compatible method for controlling hydrogel erosion rates and therapeutic agent release in keratin-based systems.

The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential and challenges for clinical application, but it reports no new clinical findings.

This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.

This study developed an all-natural hydrogel that promotes diabetic wound healing by converting pro-inflammatory M1 macrophages to anti-inflammatory M2 macrophages in a simple and biosafe manner.

This study systematically characterized the nanomechanical properties of human hair, such as hardness and elastic modulus, across different ethnicities and treatment conditions using nanoindentation and scanning electron microscopy.