38 citations
,
January 2020 in “Cell Transplantation” This study found that ACE2 and TMPRSS2 genes were more highly expressed in tumors of elderly male cancer patients compared to healthy individuals, with notable differences across age and gender.
32 citations
,
October 2004 in “Pharmacotherapy” In this study, peginterferon alfa-2b plus ribavirin therapy in hepatitis C patients was associated with serious adverse drug reactions in 20% of cases, highlighting differences from clinical trial findings.
31 citations
,
January 2011 in “Journal of Biomaterials and Nanobiotechnology” This paper describes the development of unique hydrogel skin scaffolds from plant-derived polysaccharide mixtures that may offer improved biocompatibility and mechanical properties for use in artificial skin.
27 citations
,
October 2020 in “Medical Journal of the Islamic Republic of Iran” This study found that elderly COVID-19 patients are more prone to multiorgan damage, highlighting the need for comprehensive care to lessen the disease's impact.
23 citations
,
February 2021 in “Journal of Endocrinological Investigation” This review discusses the impact of COVID-19 on the endocrine system and reports no clinical results; the authors emphasize the need to investigate endocrine damage during and after COVID-19 infection.
21 citations
,
May 2021 in “Prostate Cancer and Prostatic Diseases” This review analyzes the potential mechanisms by which SARS-CoV-2 may exacerbate symptoms of benign prostatic hyperplasia and suggests a connection via ACE2 and androgen receptor pathways; it reports no new clinical results.
21 citations
,
July 2004 in “British Journal of Dermatology” This study suggests that hair follicles in the genital area may serve as reservoirs for high-risk human papillomaviruses.
21 citations
,
September 2011 in “PubMed” This article reviews prominent variants of scalp hair folliculitis and their differential diagnosis, but reports no new clinical findings.
17 citations
,
May 2021 in “Journal of Assisted Reproduction and Genetics” This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.
14 citations
,
March 2022 in “Dermatologic Therapy” This review discusses the incidence and characteristics of COVID-19-related hair loss and highlights psychological support as crucial for recovery, but reports no new research results.
14 citations
,
July 2021 in “Reviews in endocrine and metabolic disorders” This study explores how SARS-CoV-2 interacts with endocrine organs and highlights specific endocrine molecules that help explain the progression and outcomes of COVID-19, especially in patients with certain metabolic conditions.
14 citations
,
June 2020 in “Journal of the American Academy of Dermatology” This article describes international efforts by dermatologists to launch and harmonize registries focused on COVID-19's dermatologic impacts, aiming for better global collaboration and data sharing.
14 citations
,
April 2020 in “Journal of the American Academy of Dermatology” Viral reactivation is rare at the time of DRESS diagnosis in the U.S.
14 citations
,
January 2006 in “Skinmed” A woman developed white patches on her skin and curly hair after hepatitis C treatment, likely due to the medication interferon alpha.
13 citations
,
October 2021 in “The Journal of Microbiology” This study found that human placenta hydrolysate reduced SARS-CoV-2 replication and improved immune response in ferret models, suggesting potential as a COVID-19 treatment.
13 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified four drugs, including brequinar and abiraterone acetate, that inhibited SARS-CoV-2 infection in vitro, providing potential candidates for repurposing to treat COVID-19.
12 citations
,
January 2022 in “The Egyptian Journal of Internal Medicine” This review summarizes current knowledge of SARS-CoV-2, including its biology, epidemiology, risk factors, and the need for updated vaccines and drugs, but presents no new clinical findings.
12 citations
,
January 2022 in “Journal of Menopausal Medicine” This review discusses the impact of COVID-19 on hormone therapy in gynecology, emphasizing the need for more high-quality evidence for individualized management, but it reports no new clinical results.
11 citations
,
December 2020 in “Clinics in Dermatology” This review discusses the impact of COVID-19 on dermatology practice in Iran, emphasizing adaptation to challenges such as teledermatology and new cutaneous COVID-19 symptoms, but reports no new clinical results.
10 citations
,
October 2010 in “Hepatology” This case study suggests that treatment with Pil-Food, intended for hair loss prevention, may have triggered postinfantile giant cell hepatitis with autoimmune characteristics, which showed a rapid and effective response to corticosteroid therapy.
8 citations
,
September 2023 in “International Journal of Nanomedicine” In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.
8 citations
,
December 2022 in “Nature Reviews Endocrinology” This review discusses the roles of sex hormones in COVID-19 progression and highlights conflicting evidence on their protective effects and the complexity of sex and gender influences on the disease.
8 citations
,
June 2021 in “Journal of Cosmetic Dermatology” This review details various skin manifestations linked to COVID-19 and highlights dermatitides caused by personal protective equipment, emphasizing the need for accurate diagnosis and prompt treatment.
7 citations
,
June 2021 in “JAAD Case Reports” This article reviews the cutaneous manifestations of COVID-19, highlighting their potential as early indicators of infection, and reports no new clinical results.
7 citations
,
January 2021 in “Biology” This study documented a variety of skin lesions in COVID-19 patients, indicating that skin rashes might be an early or sole symptom of the disease.
7 citations
,
December 2020 in “Endocrine-related Cancer” This article discusses the potential role of oral DHEA, available as a 'dietary supplement' in the US, in COVID-19 morbidity and mortality, calling for clinical trials to assess its safety.
6 citations
,
July 2021 in “Bulletin of the National Research Centre/Bulletin of the National Research Center” This review discusses the transmission and immune response of SARS-CoV-2 and highlights ongoing research for developing vaccines and antiviral treatments, but it presents no new clinical findings.
6 citations
,
May 2021 in “Clinical Chemistry and Laboratory Medicine” This review discusses the impact of ACE polymorphism on COVID-19 severity, suggesting it affects adults more than children, but presents mixed findings concerning infection prevalence and mortality.
6 citations
,
December 2020 in “Dermatological reviews” This review discusses the potential link between androgenic alopecia, androgens, and the severity of COVID-19, highlighting possible therapeutic targets but reports no new clinical results.
5 citations
,
December 2021 in “Physiological Research” This paper reviews the role of androgens in SARS-CoV-2 infection and their potential impact on disease severity, suggesting androgen-targeting strategies might influence outcomes, but reports no new clinical results.