research Keratin Formation in the Hair Follicle
Keratin fibrils in hair form and stop growing at specific points in the follicle.
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research Syphilitic Alopecia: Uncommon Trichoscopic Findings
New hair and skin changes were found in a rare case of syphilis-related hair loss.
research Oral Syphilis: Report of Three Cases and Characterization of the Inflammatory Cells
The document concludes that recognizing oral lesions is important for diagnosing syphilis.
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research Progesterone-Induced Stimulation of Mammary Tumorigenesis Is Due to the Progesterone Metabolite, 5α-Dihydroprogesterone (5αP), and Can Be Suppressed by the 5α-Reductase Inhibitor, Finasteride
Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
research MiR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells
miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.
research Enhanced Skin Permeation of 5α-Reductase Inhibitors Entrapped into Surface-Modified Liquid Crystalline Nanoparticles
Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.
research Hair Follicle Mesenchymal Stem Cell Exosomal LncRNA H19 Inhibited NLRP3 Pyroptosis to Promote Diabetic Mouse Skin Wound Healing
A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
research Genomewide Differential Expression Profiling of Long Non-Coding RNAs in Androgenetic Alopecia in a Chinese Male Population
Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research Topical Treatment with the Bacterium-Derived c-Met Agonist InlB321/15 Accelerates Healing in the Abrasion Wound Mouse Model
Applying InlB321/15 to wounds sped up healing in mice.
research Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells
Hair follicle stem cells need all reprogramming factors to become pluripotent.
research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing Beta-Catenin
Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
research Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles
Certain genetic variants linked to immune response increase the risk of alopecia areata in Taiwanese people.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
research Chinese SLE Treatment and Research Group Registry XIII: Prevalence and Risk Factors for Chronic Scarring Alopecia in Patients with Systemic Lupus Erythematosus
About 8% of people with systemic lupus erythematosus have chronic scarring alopecia, with certain symptoms and positive antibodies increasing the risk, while immunosuppressants may lower it.
research Traditional Knowledge Digital Library: The Challenges Ahead
The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.
research 31-Year-Old Woman With Chronic Daily Headache and Alopecia
A woman's chronic headaches and hair loss were cured by treating her syphilis.
research Assessment of the Mean Platelet Volume-to-Platelet Count Ratio in Alopecia Areata: A Retrospective Case Control Study
The MPV/PC ratio can help assess disease activity in alopecia areata.
research Would You Recognize This Lesion as a Gumma Syphilitica?
LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
research Wnt/β-Catenin and ERK Pathway Activation: The Possible Mechanism of Various LED Light Regulating the Proliferation of Human Outer Root Sheath Cells
LED light helps human hair root cells grow and move by activating certain cell pathways.
research Wnt/B-Catenin and ERK Pathway Activation: The Possible Mechanism of Various Light-Emitting Diode Light Regulates the Proliferation of Human Outer Root Sheath Cells
LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.
research Dermatologic Care of the Transgender Patient
Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.
research News in Brief
Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.
research Secondary Syphilis in a 12-Year-Old Girl Misdiagnosed as Pityriasis Lichenoides et Varioliformis Acuta: A Case Report
Syphilis should be considered if PLEVA-like symptoms don't improve with treatment.
research Podophyllotoxin-Loaded Solid Lipid Nanoparticles for Epidermal Targeting
P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
research OsCSLD1 Mediates NH4+-Dependent Root Hair Growth Suppression and AMT1;2 Expression in Rice
CSLD1 suppresses rice root hair growth with NH4+ and regulates AMT1;2 expression.
research Micropigmentation
Micropigmentation is a cosmetic tattooing technique for hiding skin issues and creating permanent makeup, but it can have side effects.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Pharmaceutical Nanotechnology in Egypt: Diverse Applications and Promising Outcomes
Egyptian researchers are advancing in pharmaceutical nanotechnology, potentially improving health outcomes and the economy.