research Alopecia Universalis Successfully Treated With Adalimumab
A woman with severe hair loss was successfully treated with the drug adalimumab.
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research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Pharmacology of Natural Volatiles and Essential Oils in Food, Therapy, and Disease Prophylaxis
Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
research Induction of T Cell Exhaustion by JAK1/3 Inhibition in the Treatment of Alopecia Areata
Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
research Long-Term Efficacy and Safety of Baricitinib in Patients With Severe Alopecia Areata: 104-Week Results From BRAVE-AA1 and BRAVE-AA2
Baricitinib is effective and safe for long-term use in severe alopecia areata, improving hair regrowth and quality of life with few side effects.
research Neuropathic Pruritus: An Underrecognized and Often Misdiagnosed and Difficult to Treat Medical Condition
Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.
research Surgical Management Of Scarring Alopecia
Hair loss due to scarring can be treated by reducing inflammation, removing scar tissue, and transplanting hair. The Follicular Unit Extraction technique is effective but requires skill and time. Future focus should be on scar-less healing methods.
research Omenn Syndrome in a 10-Month-Old Male With Athymia and VACTERL Association
A 10-month-old boy with a rare combination of genetic conditions has severe immune deficiency and treatment challenges.
research Disease Prevention and Alleviation by Human Myoblast Transplantation
Myoblast transplantation shows promise for treating various muscle and heart conditions.
research 9-cis-Retinoic Acid Capsules in the Treatment of AIDS-Related Kaposi Sarcoma
9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.
research Oral Lichen Planus: A Chronic Systemic Disease with Immune-Mediated Pathogenesis
Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.
research A Novel In Vivo Active Pemphigus Model Targeting Desmoglein 1 and Desmoglein 3: A Tool Representing All Pemphigus Variants
New mouse models of Pemphigus show severe symptoms and need better treatments.
research Challenges Associated With the Identification of Germline Variants on Myeloid Malignancy Genomic Profiling—A Singaporean Experience
Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.
research Monotherapy for Alopecia Areata: A Systematic Review and Network Meta-Analysis
Intralesional corticosteroids work best for mild alopecia areata, and DPCP works best for moderate to severe cases.
research Efficacy and Safety of Topical Rosuvastatin and Melatonin vs. Placebo in Patients with Mild to Moderate Plaque Psoriasis: A Preliminary Randomized Double-Blinded Clinical Trial
Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
research Platelet-Rich Plasma for the Treatment of Androgenetic Alopecia: A Patient Survey
PRP treatment for hair loss shows promise, with 58% of patients satisfied and most noticing improvement within 6 months.
research The Effect of Cilostazol on Hair Growth: A Novel Therapeutic Option for the Treatment of Hair Loss
Cilostazol may help hair grow and could be a new treatment for hair loss.
research Effect of Prostaglandin D2 on Hair Follicle Growth and Its Impact on Hair Follicle Stem/Progenitor Cells
Blocking Prostaglandin D₂ may help treat hair loss.
research PLAU and SerpinB2 Role in Apoptosis in Leprosy
PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.
research Dermal Wnt/β-Catenin Signaling Controls Hair Follicle Dermal Condensate Size During Development
Dermal Wnt/β-catenin signaling is important for the proper size and development of hair follicles.
research Effect of Lithocholic Acid as a Ligand of Vitamin D Receptor on Hair Growth in Alopecia
Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
research Signaling Networks Between Stem Cell Precursors, Transit Amplifying Progenitors, and Their Niche in Developing Hair Follicles
Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
research Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia
Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
research Medical Education and Care in Dermatology During the SARS-CoV-2 Pandemic: Challenges and Opportunities
The pandemic has pushed dermatology education and care to adopt digital solutions, which are effective and likely to continue post-pandemic.
research Linear Morphea with Evidence of Hair Regrowth
Topical treatments led to hair regrowth in a man with linear morphea.
research Follicular Disorders: Pathogenesis, Clinical Features, Diagnosis, and Treatment
The document concludes that proper diagnosis and treatment of follicular disorders are crucial, with specific treatments for conditions like acne, drug-induced eruptions, and rosacea.
research Lupus Erythematosus: Considerations About Clinical, Cutaneous, and Therapeutic Aspects
Lupus treatment requires a combination of drugs and therapies, with research needed for new options.
research An Open Label Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
research Tendency to Underestimate the Severity of Androgenetic Alopecia
People often underestimate hair loss severity, with fewer seeking treatment, and it's more distressing for women.