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Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Humans lost body hair relatively recently in evolution.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Sponge helps heal wounds faster with less inflammation and better skin/hair growth.

Skin has specialized touch receptors that can tell different sensations apart.