11 citations
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September 2012 in “Journal of Nanjing Medical University” In this study, cyclosporine A stimulated hair growth in mouse vibrissae organ culture by promoting matrix cell proliferation and altering growth factor expression.
7 citations
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January 2022 in “Molecules” This study found that tectoridin, an isoflavone from Rhizoma Belamcandae, may stimulate hair growth by activating Wnt signaling in human and mouse cell cultures.
January 2025 in “Nature Communications” Using synchrotron X-ray imaging, this study mapped the complex innervation of male rat vibrissa follicles, revealing distinct types of myelinated afferent neurons and patterns of axonal organization that may inform sensory processing in the brainstem.
January 2019 in “Deleted Journal” This in vitro study suggests that Biofield Energy Healing Treatment may promote hair growth as evidenced by increased telogen formation in vibrissae hair follicle organ culture cells.
1 citations
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December 2001 in “Linchuang pifuke zazhi” In this study, certain Chinese herbal medicines were found to significantly stimulate or inhibit hair growth in an in vitro organ culture model of mouse vibrissa follicles.
1 citations
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January 1993 in “Skin Pharmacology and Physiology” This study found that an extracellular calcium binding site gradient exists in mouse vibrissa and human scalp follicles, but is not significantly affected by hair growth-altering drugs or epidermal growth factor.
July 2024 in “Journal of Nanobiotechnology” This study found that dermal papilla cell-derived exosomes promote hair follicle regeneration during wound healing by enhancing fibroblast activity and activating the Wnt/β-catenin signaling pathway in mice.
January 1992 in “Biology of the Cell” Retinoic acid receptors are important for hair follicle development.
6 citations
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July 2021 in “The anatomical record” This study described the diverse vibrissal follicle anatomy in fetuses of three cetacean species and observed species-specific differences, supporting further investigation into vibrissal form and function across cetaceans.
July 2026 in “Journal of the American Academy of Dermatology” 18 citations
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October 1978 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that excess vitamin A induced stable glandular morphogenesis and mucous metaplasia in embryonic mouse vibrissa follicles, even after switching to standard medium.
1 citations
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October 2015 in “OakTrust (Texas A&M University Libraries)” This study found that harp seal vibrissal innervation studies focusing only on lateral vibrissae may overestimate total innervation by about 20%, highlighting the importance of considering the entire snout.
39 citations
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April 1992 in “Development” In this study, researchers detailed how hair follicles regenerate after microsurgical amputation, observing a wound reaction involving dynamic dermal-epidermal interactions and changes in extracellular matrix components.
25 citations
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July 2004 in “Experimental Dermatology” This study found that water-soluble extracts of Illicium anisatum promoted hair follicle elongation in cultured mouse vibrissae, suggesting potential use in hair growth products.
10 citations
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January 2014 in “BioMed research international” In this study, dermal papilla cells from rat vibrissae showed potential for treating CNS injuries by secreting neurotrophic factors and promoting neuronal differentiation more effectively than bone marrow mesenchymal stem cells.
7 citations
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April 2000 in “Mammalian Genome” This study identified a new mutation in SELH/Bc mice causing distinctive whisker and body hair abnormalities, mapped near the type I keratin cluster on chromosome 11.
July 2025 in “Communications Biology” In this study, researchers used synchrotron X-ray imaging to examine rat vibrissa follicles, finding that despite variations in vibrissa length and follicle size, certain sensory structures remain consistent, suggesting specialized roles in sensory processing depending on the vibrissa type.
This study found that stem cells from mouse dental pulp and vibrissae shared similar marker profiles, but dental pulp stem cells expressed a broader range of stem cell markers, suggesting their potential use in regenerative medicine.
This study suggests that keratin 15 and Id3 proteins play distinct roles in epithelial and dermal cell activities during the regeneration stages of rat vibrissae hair follicles.
59 citations
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August 2003 in “Phytotherapy Research” This study found that a 70% methanol extract from red ginseng stimulated hair growth in mouse vibrissal follicles, suggesting its bioactive components, particularly certain ginsenosides, may promote hair growth.
1 citations
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October 2001 in “Journal of Wood Science” This study found that extracts from the fungus YL161, Agaricus blazei, and the bark of Camptotheca cuminata promoted dermal papilla cell growth more effectively than pentadecanoic acid, suggesting potential for stimulating hair growth.
5 citations
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January 2016 in “Journal of Molecular Histology” Both main and alternative Wnt signaling are important for regrowing rodent whisker follicles.
January 2005 in “Pharmaceutical Journal of Chinese People's Liberation Army” In this study with cultured C_57BL/6J mouse hair follicles, ginseng extract at a concentration of 0.1 mg/ml was reported to best promote hair growth.
46 citations
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January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
28 citations
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October 2011 in “International Journal of Molecular Medicine” In this study, adenosine was found to stimulate hair follicle growth in vitro by promoting growth factor expression, β-catenin activation, and downstream signaling pathways.
24 citations
,
July 1994 in “Journal of Investigative Dermatology”
520 citations
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February 2001 in “Journal of Clinical Investigation” This study found that VEGF significantly enhances perifollicular vascularization during the hair growth phase, accelerating hair regrowth and increasing follicle and hair size, while its inhibition retards hair growth.
128 citations
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March 1989 in “Experimental Cell Research” Hoxc13 is important for hair and tongue development by controlling hair keratin genes.
68 citations
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December 1991 in “Annals of the New York Academy of Sciences” Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
64 citations
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May 2015 in “Cell Cycle” This study found that hair follicle stem cells from mice can differentiate into beating cardiac muscle cells, suggesting potential applications for heart regeneration in regenerative medicine.