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New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

New technologies help us better understand how skin microbes affect skin diseases.

Gentamicin penetrates pig skin better through open hair follicles than blocked ones.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

Using micro skin tissue columns improves skin wound healing and reduces scarring.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.

AcSDKP may help prevent skin and hair aging and promote their growth.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

The natural topical treatment improved rabbits' skin and hair condition.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.

Using sonophoresis can make it harder for certain drug-loaded liposomes to get through the skin.

Microneedle technology is effective for skin rejuvenation and enhancing cosmeceutical delivery, with ongoing innovation and increasing commercialization.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

Active transdermal technologies in cosmetics help deliver skin treatments effectively, but their safety and effectiveness depend on skin type and treatment choice.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

PEVs effectively deliver minoxidil through skin.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

Niosomes are a promising and effective way to deliver drugs through the skin.

Deer antler velvet serum helps hair grow and is safe for skin.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Herbal nano-formulations show potential for effective skin delivery but need more research.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.