152 citations
,
April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
46 citations
,
April 2009 in “Journal of Dermatological Case Reports” This study established standard trichoscopy norms for adult white females, providing benchmarks for hair thickness, percentage of thin hairs, and pilosebaceous units with single hair across different scalp areas.
43 citations
,
April 2021 in “Angiogenesis” This review examines the evolving understanding of lymphatic vessel development, emphasizing new cellular mechanisms and lineage diversity, while discussing experimental methods and identifying key knowledge gaps.
27 citations
,
June 2019 in “Aesthetic Plastic Surgery” Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.
21 citations
,
June 2018 in “Current Opinion in Genetics & Development” This review discusses recent advancements in regenerative medicine, including functional organ regeneration and the creation of mini-organs, and reports no new clinical results.
16 citations
,
February 2018 in “Journal of The American Academy of Dermatology” This study found that scalp involvement in dermatomyositis consistently shows a nonscarring pattern with chronic telogen effluvium, featuring telangiectasia and mucin deposition as universal histologic markers.
11 citations
,
October 2020 in “Sensors” This study found that photoacoustic imaging can effectively measure follicle density and angles, even when follicles are not visible to the eye, providing a promising alternative to traditional photographic examination.
8 citations
,
January 2016 in “Journal of Veterinary Medical Science” This study found that canine adipose-derived mesenchymal stem cell-derived dermal papilla-like tissues promoted new hair follicle formation and increased vascularization in mice, suggesting potential for hair regeneration.
3 citations
,
March 2017 in “Case Reports in Dermatology” This case report describes a 26-year-old with systemic lupus erythematosus presenting with psoriatic alopecia, revealing a novel scalp dermoscopic pattern of “patchy dotted vessels.
3 citations
,
October 1982 in “Postgraduate Medicine” This article discusses objective methods for assessing hair loss and notes that most types of hair loss can regrow without treatment, but effective treatments for pattern or senescent alopecia remain unavailable.
1 citations
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May 2022 in “Frontiers in medicine” This study found that topical application of metformin significantly enhanced skin regeneration in mechanically stretched skin in rats, likely by boosting the proliferation of skin-derived stem cells.
1 citations
,
January 2001 in “Dermatologic Surgery” Pulsed dye laser and hydrogel dressings effectively treat hypertrophic scars.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
January 2019 in “Springer eBooks” Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
This study found that dermal papilla-like tissues derived from canine adipose stem cells promoted new hair follicle formation and increased vascularization in athymic nude mice.
September 2014 in “Springer eBooks” Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
76 citations
,
March 2005 in “Cancer Research” This study in ND-GFP transgenic mice found doxorubicin inhibited both tumor angiogenesis and growth, visualized through dual-color fluorescence imaging of nascent blood vessels and melanoma cell lines.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.
36 citations
,
June 2014 in “PLOS ONE” This study found that men with persistent sexual side effects after using finasteride for androgenetic alopecia had higher androgen receptor expression in certain tissues compared to those who never used the drug.
34 citations
,
April 2016 in “International Journal of Dermatology” In this study, certain trichoscopic features were found to be sensitive and specific for diagnosing primary cicatricial alopecias and its subtypes using dermatoscopy.
29 citations
,
January 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that trichoscopic examination is useful for diagnosing and monitoring systemic lupus erythematosus, with severe diffuse non-scarring alopecia indicating active disease.
8 citations
,
January 2021 in “Smart materials in medicine” This study found that a newly constructed composite hydrogel dressing, made from silk fibroin, chitosan, and halloysite, promoted hair follicle neogenesis, angiogenesis tissue regeneration, and scar reduction.
June 2023 in “Research Square (Research Square)” This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.
October 2021 in “Journal of Investigative Dermatology” This study found no significant difference in SARS-CoV2 IgG seroconversion rates between patients with immune-mediated inflammatory diseases treated with targeted immune-modulating therapies and those on conventional systemic treatments.
In this study, Minoxidil and other treatments prevented alopecia in mice induced by Paclitaxel, with quantitative data supporting the inhibition of hair loss.
24 citations
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November 2013 in “Molecular Medicine Reports” This study demonstrated that human hair follicle stem cells can be efficiently differentiated into endothelial-like cells using VEGF and bFGF, suggesting their potential as a novel cell source for vascular tissue engineering.
12 citations
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February 2023 in “Stem Cell Research & Therapy” This study found that injecting hepatocyte growth factor-enhanced hair follicle stem cells into a rat model of ischemic stroke improved recovery by reducing inflammation, protecting the blood-brain barrier, and promoting angiogenesis.
3 citations
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April 2020 in “Medicine” This study is set to explore acupuncture's effects on seborrheic alopecia through a randomized controlled trial, aiming to assess its clinical effectiveness and safety.
This review discusses platelet-rich plasma therapy for hair loss and reports no new clinical results, highlighting its potential benefits, mechanisms of action, and areas needing further research.
214 citations
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September 2015 in “Stem Cells Translational Medicine” This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.