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Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.

PRP helps skin heal, possibly through special cells called telocytes.

Not getting enough minerals can lead to health problems and shorter lifespans.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.

Some women with PCOS have rare genetic variants linked to the condition.

Insulin might be involved in causing hair loss and acne.

Platelet Rich Plasma-Derived Extracellular Vesicles show promise for healing and regeneration but need standardized methods for consistent results.

Fewer GGC sequences in the androgen receptor gene improve finasteride treatment for hair loss.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Nourkrin® with Marilex® may significantly increase hair growth and alopecia could be an early sign of metabolic syndrome.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Lasers are effective and safe for various medical treatments, including cancer, wound healing, and skin conditions.

New drug delivery methods can make natural compounds more effective and stable.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

New treatments for male hypogonadism are effective and should be personalized.

Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.

MK-R7 supplement with Cistanche Tubulosa and Laminaria Japonica extracts improved hair density and scalp health without adverse effects.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.