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Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Use minoxidil for hair loss treatment; assess results after 6 months.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.