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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Women with PCOS who had antiandrogenic treatment before pregnancy had fewer complications than those without treatment.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Finasteride has a higher risk of reproductive side effects than minoxidil.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.

Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Tamoxifen caused hair loss in a 52-year-old woman.

Platelet-rich treatments can help improve wound healing and tissue repair.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

People with alopecia areata have higher rates of mental health issues, autoimmune diseases, and infections.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

The conclusion is that more research is needed to better understand and treat adult acne, and that patient education and simple treatment plans are important for better results.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.