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Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

PCOS is a hormonal disorder causing infertility and menstrual problems, often linked to obesity and can lead to acne, treated with hormonal and insulin-sensitizing medications.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Caucasian and Asian women with PCOS generally show similar symptoms, except Asian women have less chest hair.

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Women with PCOS have lower amylin levels, which are not related to their body weight.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.