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Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Humans lost body hair relatively recently in evolution.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Eczema and fungal infections are the most common skin problems in Japan, with different age groups and genders affected by various conditions.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Understanding hair follicle anatomy helps diagnose hair disorders.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

TSH is usually the only test needed to check thyroid function in primary care.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.