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Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.

Early NAS level changes affect alcohol consumption vulnerability.

Women may need different blood pressure guidelines than men for heart disease prevention.

A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.

Whale genes show changes that help them live in water, like less hair and better flippers.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Some drugs can cause hair loss, excessive growth, or color changes, often reversible but sometimes permanent.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Human hair protein modifications could potentially indicate heart disease risk.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.

Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.

Gut microbes significantly affect brain steroid levels.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

The document says that there are treatments for hair and nail diseases.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.