This study developed a three-dimensional model for studying hair follicle development, showing that immortalized dermal papilla cells retain certain differentiation activities and can induce tubule formation in vitro.
37 citations
,
October 2017 in “Clinical and Experimental Dermatology” This article discusses the potential of oral tofacitinib as a treatment for atopic dermatitis, alopecia areata, and vitiligo, without presenting new clinical results.
25 citations
,
April 2019 in “Journal of The American Academy of Dermatology” This study discusses the role of CD8+ T-cell and interferon γ signaling in vitiligo's pathogenesis and notes that JAK inhibitors, which are FDA-approved for other autoimmune diseases, may offer a potential treatment path by blocking this pathway.
5 citations
,
June 2024 in “Archives of Dermatological Research” This study found that fractional Er:YAG laser combined with platelet-rich plasma resulted in greater skin repigmentation in patients with localized stable vitiligo compared to microneedling with platelet-rich plasma, with fewer side effects reported in the laser group.
August 2025 in “Indian Dermatology Online Journal” This study found that combining topical minoxidil with phototherapy significantly improved pigmentation and reduced vitiligo severity compared to placebo, as measured by VASI scores over 12 weeks, though the sample size was small and follow-up short.
5 citations
,
January 2025 in “BMC Medical Informatics and Decision Making” This review examines the use of computer vision techniques, specifically deep learning architectures and image processing algorithms, for detecting and assessing skin conditions like vitiligo and dermatitis, and highlights the need for disease-specific datasets to improve automated diagnostic tools in dermatology.
1 citations
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July 2024 in “Journal of Investigative Dermatology” VYN201 shows promise as a safe and effective treatment for non-segmental vitiligo.
May 2026 in “Southeast Asian Journal of Case Report and Review” In this study, individualized homoeopathic treatment with Silicea showed a marked reduction in depigmentation for a case of vitiligo, with a likely causal link suggested by evaluation criteria.
January 2021 in “Benha Journal of Applied Sciences” This study found no significant difference in serum prolactin levels between vitiligo patients and healthy controls, nor any significant association between prolactin gene polymorphism and vitiligo severity, except for a significant relation with BMI.
November 2021 in “CRC Press eBooks” This article reviews anagen effluvium, a type of non-scarring alopecia that affects both men and women, often induced by chemotherapy or radiation, and discusses diagnostic approaches but reports no new clinical findings.
328 citations
,
November 2020 in “Nature Materials” This study found that D-peptide crosslinked MAP hydrogel accelerated material degradation in vivo but significantly enhanced skin regeneration, suggesting an adaptive immune response can drive regenerative healing even with rapid scaffold breakdown.
119 citations
,
February 2009 in “Neuroscience & Biobehavioral Reviews” This review discusses the psychological and neurobiological aspects of trichotillomania and reports no new results, emphasizing the need for further research on its treatment and neural mechanisms.
71 citations
,
May 2024 in “New England Journal of Medicine” This study investigated the impact of the JAK inhibitor ruxolitinib on APS-1 patients, reporting that treatment decreased excessive T-cell-derived interferon-γ, normalized inflammatory markers, and led to remission of several autoimmune symptoms without serious adverse effects.
67 citations
,
June 2018 in “Engineering in Life Sciences” This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.
62 citations
,
June 2011 in “Lupus” This study found that male patients with systemic lupus erythematosus had a higher prevalence of certain complications like thromboses and nephropathy than female patients, suggesting gender influences the disease's clinical expression.
57 citations
,
January 2022 in “Biomedicines” This review outlines curcumin's dual role as a radiosensitizer in cancer cells and a radioprotector in healthy cells, drawing on recent experimental and clinical findings.
55 citations
,
July 2016 in “Eye”
50 citations
,
June 1999 in “Annals of Oncology” This study found that long-term weekly administration of docetaxel is feasible at doses up to 45 mg/m² per week with acceptable toxicity, and suggests further evaluation with 40 mg/m² for phase II studies.
47 citations
,
December 2021 in “Applied Sciences” This study demonstrated that Stellaria media extract may enhance wound healing in vitro by promoting cell migration and proliferation, with notable antioxidant and antimicrobial properties.
37 citations
,
May 2021 in “Frontiers in Cell and Developmental Biology” This study found that Ng2+ perivascular cells in mouse skin are a diverse lineage-restricted population primarily recruited from papillary or reticular fibroblast lineages during wound healing, maintaining heterogeneity in both wounded and non-wounded skin.
35 citations
,
October 2021 in “Journal of the European Academy of Dermatology and Venereology” This report describes two cases where a viral vector COVID-19 vaccine was associated with the recurrence of cutaneous lymphoma conditions that had been in remission.
31 citations
,
January 2016 in “Skin Appendage Disorders” This study observed two cases of frontal fibrosing alopecia developing on preexisting vitiligo, suggesting a potential causal link between the two conditions.
21 citations
,
November 2015 in “Archives of Gynecology and Obstetrics” Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
19 citations
,
January 2017 in “Hormone Molecular Biology and Clinical Investigation” This study found a high prevalence of hyperandrogenemia in women with PCOS, with distinct biochemical differences according to BMI and presence of hyperandrogenemia.
16 citations
,
July 2012 in “Current pharmaceutical biotechnology” This review discusses the pathogenesis of common sebaceous gland diseases and their molecular pathways, but it reports no new clinical findings.
16 citations
,
January 2012 in “European Journal of Endocrinology” This study reports an increased frequency of the DI genotype of the ACE gene polymorphism among women with PCOS, notably in those with hyperandrogenism, and an association of the II genotype with insulin resistance.
14 citations
,
June 2021 in “British journal of dermatology/British journal of dermatology, Supplement” This paper presents consensus guidelines for standardized diagnostic criteria and assessment methods for frontal fibrosing alopecia to improve clinical research and data collection globally.
13 citations
,
September 2021 in “Communications Biology” This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.
13 citations
,
July 2018 in “Obesity surgery” This study found that 56% of patients experienced hair loss six months after undergoing laparoscopic sleeve gastrectomy, with lower preoperative and postoperative zinc and vitamin B12 levels associated with this outcome.
12 citations
,
October 2018 in “Journal of Mind and Medical Sciences” This study found that an unhealthy lifestyle, including factors like past smoking and lack of fruit/vegetables in the diet, was associated with an increased risk of metabolic syndrome.