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This study found that a specific Gli1+ subpopulation in the perivascular niche plays a crucial role in wound healing by differentiating into myofibroblasts, with their genetic ablation impairing wound repair.

This review explores the cellular dynamics of graft rejection in vascularized composite allotransplantation and discusses how understanding these processes might lead to innovative treatments for managing rejection.

This study found that conditioned medium from placental cells and sub-cultured placental tissue promoted angiogenesis in human umbilical vein endothelial cells in vitro, with early pregnancy cells having a more significant effect.

This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.

In this study, researchers suggest that strategic early intervention during fetal wound healing could lead to significantly improved long-term skin regeneration outcomes.

This study found that transplanting human cord blood mononuclear cells transfected with a plasmid encoding VEGF and FGF2 into rat skin wounds may accelerate the wound healing process.

This article reviews the classification and treatments of vascular anomalies, such as hemangiomas and vascular malformations, and reports no new clinical results; it emphasizes the importance of managing patient expectations due to treatment limitations.

This study observed that using transfected human cord blood cells enhanced skin wound healing in rats by promoting angiogenesis and earlier termination of proliferation compared to untransfected cells.

This study found that the acceleration of endothelial to mesenchymal transition due to loss of Notch signaling led to delayed wound healing and increased scarring in skin wounds.

This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.

In this study, epidermal stem cells were found to enhance blood vessel formation and support successful one-step transplantation of tissue-engineered skin in a rat model.

This study found that micro-CT imaging can effectively identify vascular structures in rat models of congenital hypospadias, providing anatomical insights for selecting preputial vessel flaps in surgical procedures.

In this study, researchers developed a novel method using ultrasound stimulation and a hydrogel delivery system to enhance the regenerative effects of stem cell-derived extracellular vesicles on severe skin injuries, resulting in improved healing and hair follicle regeneration in a mouse model.

This study found that human fetal CD133+ progenitor cells and their conditioned medium accelerated wound healing and promoted angiogenesis in a mouse model of ischemic diabetic ulcers through paracrine mechanisms involving Wnt signaling.

This study demonstrated that human hair follicle stem cells can be efficiently differentiated into endothelial-like cells using VEGF and bFGF, suggesting their potential as a novel cell source for vascular tissue engineering.

This study used multi-scale hybrid models to explore how signaling factors affect skin wound healing and embryo development, suggesting that different levels of fibrin clot density influence scar formation.

This study demonstrated that prevascularized human skin constructs containing engineered hair follicles can successfully induce human hair growth when grafted onto mice by promoting blood supply to the grafted skin.

This study found that controlled release of VEGF via a collagen hydrogel promoted hair follicle growth and cell proliferation in mice more effectively than free VEGF injections.

This study demonstrates that transfected epidermal stem cells using a novel 3D transfection system significantly enhanced wound healing and may serve as an effective therapeutic agent and gene delivery method for wound treatment.

This review explores the role of lymphatic vessels in skin regeneration and hair follicle growth, emphasizing their interactions with hair follicle stem cells and potential implications for regenerative therapies, but reports no new clinical results.

This study highlights that a novel radially aligned nanofiber scaffold with dual growth factor gradients significantly enhances wound healing, promoting cell migration, epidermal regeneration, and angiogenesis, ultimately leading to improved wound closure, immune regulation, and tissue remodeling compared to other groups.

This study observed that tissue-engineered skin, using VEGF165 gene-modified cells embedded in astragalus polysaccharide-containing 3D printed scaffolds, enhanced early vascularization, and collagen and hair follicle regeneration, leading to improved skin repair in nude mice with full skin defects.

This review covers the potential of SVF and ADSC therapies in regenerative medicine and highlights the challenges of regulation and efficacy, without reporting new clinical results.

In this study, xenobiotic-free human multipotent adult progenitor cells were found to improve wound vascularization and healing in mice, suggesting potential applicability for clinical use in humans.

This study found that low oxygen conditions and ECM degradation products increased the proliferation and migration of perivascular stem cells without altering their phenotype, suggesting potential roles in tissue repair.

This research found that LSE transplantation positively affects wound healing by promoting granulation tissue growth and minimizing cosmetic defects in ischemic non-healing wounds during preclinical studies. Additionally, the proposed smoothing coefficient helps assess the degree of wound bed filling with developing tissue.

This study found that combining ultrasound with a GelMA hydrogel able to deliver mesenchymal stem cell-derived vesicles significantly improved wound healing in a mouse model by enhancing fibroblast activity, promoting re-epithelialization, and facilitating hair follicle regeneration, highlighting a novel approach to skin regeneration therapy.

This study demonstrated that EVs from pluripotent stem cell-derived mesenchymal stem cells improved recovery and function in ischemic lower limbs by enhancing angiogenesis through the ERK/MAPK signaling pathway.

This study found that perifollicular vascularization around the dermal papilla adjusts dynamically to physiological changes, with minoxidil enhancing vessel mobilization and aging processes inhibiting it, highlighting potential targets for treating hair loss and skin aging.

This study presents a detailed overview of lymphatic vessel development and highlights the role of abnormal lymphangiogenesis in various diseases, suggesting that targeting lymphangiogenic factors may improve treatment strategies.