2 citations
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November 2022 in “Scientific reports” This study found that gelatin sponges used as scaffolds in rats with deep wounds and periosteal defects enabled regeneration of diverse tissue types, including periosteum, skin, and appendages, highlighting the role of vascular niche formation.
March 2023 in “Institutional Repositories DataBase (IRDB)” 69 citations
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October 2013 in “Journal of Tissue Engineering and Regenerative Medicine” This review examines the role of endothelial precursors and cellularized scaffolds in wound repair and revascularization for treating full thickness skin loss, but reports no new clinical results.
23 citations
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February 2025 in “Advanced Materials” This study found that a new autonomous, moisture-driven flexible electrogenerative dressing significantly accelerated chronic wound healing in a diabetic mouse model compared to the control group.
3 citations
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May 2021 in “Dermatologic Clinics” This article reviews potential therapeutic targets and comorbidities associated with male androgenetic alopecia, but reports no new clinical results; further study is needed for comprehensive management.
February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
December 2021 in “Research Square (Research Square)” In this study, high expression of S100A4 in glioblastoma was associated with worse patient survival and promoted tumor progression by enhancing pro-tumorigenic vascular functions.
37 citations
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February 2024 in “Military Medical Research” In this review, biomaterial-based mechanical strategies were highlighted for their potential to enhance skin regeneration and promote scarless repair, though a comprehensive understanding of their underlying mechanisms is still needed for broader application.
July 2010 in “Journal of Investigative Dermatology” Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers observed that blood vessel maturation in mice involves neonatal endothelial cells expanding the capillary network through vessel regression and angiogenesis, with adult cells later maintaining stability and repair through specific signaling pathways.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that mice lacking epidermal HSD11b1 had increased non-histaminergic itch and changes in skin nerve fibers, potentially linked to higher TSLP expression.
29 citations
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May 2023 in “Cell” 212 citations
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August 2004 in “Proceedings of the National Academy of Sciences” This study found that nestin-driven GFP labels blood vessels originating from hair follicles in mice, which could be used to study early events in skin angiogenesis and for antiangiogenesis drug screening.
October 2024 in “African Journal of Medicine Surgery and Public Health Research” In this review, the authors discuss how both genetic and epigenetic factors influence the development of vascular systems, highlighting the natural and pathological roles of angiogenesis in processes like pregnancy and diseases such as cancer and diabetes.
1 citations
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November 2001 in “British Journal of Dermatology” Oral cyclosporin doesn't stop hair loss.
August 2004 in “Journal of the American College of Surgeons” Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.
April 2017 in “Plastic and Reconstructive Surgery – Global Open” In this study, researchers developed a 3D-printed vascular model to analyze how different shear stresses influence cell behavior and promote cellular organization around neovessels, offering insights into tissue engineering for wound reconstruction.
This study observed that hair follicle cycling in mouse skin involves physiological vascular remodeling, with VEGF playing a key role, suggesting potential therapeutic approaches for hair growth disorders.
48 citations
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May 2002 in “Journal of Anatomy” The researchers reported that VEGF increases vascular permeability in mesenteric microvessels of anaesthetized frogs through specific cellular pathways involving tyrosine autophosphorylation and PLC activation.
24 citations
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March 2010 in “Journal of Cellular Biochemistry” This study found that an inter-hair-follicle blood vessel network, originating from ND-GFP-expressing stem cells, contributes to angiogenesis in skin transplants and wound healing in ND-GFP transgenic mice.
48 citations
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July 2008 in “Acta Biochimica et Biophysica Sinica” This review discusses the roles and mechanisms of Wnt signaling in embryonic and adult stem cells and its association with cancers, and reports no new experimental findings.
6 citations
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August 2007 in “Journal of Surgical Research” In this study, constitutive expression of Del1 in mice did not affect wound healing but was associated with increased hair growth following anagen induction.
4 citations
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January 2021 in “Journal of Clinical Medical Research” This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.
2 citations
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January 2015 in “BioMed Research International” This article reviews various aspects of growth factor research, highlighting their role in treatments and emphasizing the need for further clinical trials to validate their efficacy in biomedical applications.
1 citations
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July 2018 in “Journal of dermatology & cosmetology” This case report describes a treatment approach for frontal and temporal alopecia using oral dutasteride, minoxidil lotion, and triamcinolone injections, with hyaluronic acid successfully treating injection site atrophy.
21 citations
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April 2021 in “Biofabrication” This study developed a vascularized full-thickness skin equivalent with a complex vascular network, enhancing its predictiveness for topical and systemic drug applications in dermatology research.
160 citations
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January 2017 in “Development” This study found that hypertrophic chondrocytes at the fracture callus border may convert to osteoblasts, influenced by vasculature and pluripotency gene expression.
322 citations
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January 1997 in “Thrombosis and Haemostasis” This review discusses factors influencing angiogenesis, focusing on vascular permeability factor as a key inducer and thrombospondin as a notable inhibitor, and recommends exploring molecular mechanisms for therapeutic interventions.
29 citations
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October 2010 in “Acta Biomaterialia” 36 citations
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February 2017 in “Journal of Cellular and Molecular Medicine” In this study, VEGF165 induced hair follicle stem cells to differentiate into vascular endothelial cells, potentially supporting angiogenesis and neovascularization, with the Notch signaling pathway affecting differentiation efficiency.