November 2025 in “ACS Omega” This study found that incorporating Canavalia ensiformis lectin into alginate and carboxymethylcellulose films enhanced angiogenic factor expression, suggesting these biopolymer films could be an effective alternative for wound treatment.
12 citations
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October 2019 in “Experimental Dermatology” This study found that boehmite accelerates hair regrowth by promoting human dermal papilla cell proliferation and enhancing signaling pathways involved in the hair follicle cycle.
April 2015 in “MOJ Cell Science & Report” This study found that rat hair follicle stem cells can be effectively transfected with VEGF 165 using lentivirus vectors, suggesting their potential use in developing tissue-engineered skin with improved vascularization.
March 2026 in “Chemical Engineering Journal” The hydrogel helps heal diabetic wounds by combining antibacterial, antioxidant, and immune-boosting effects.
1 citations
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January 2020 in “Bioscience Reports” This study found that prolonged use of finasteride in women led to altered levels of sex steroids, DNA damage, and increased menstrual bleeding, suggesting adverse health effects without clear benefits for androgenetic alopecia treatment.
July 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)” This article reviews the effects of minoxidil on hair growth, highlighting its ability to stimulate hair follicle proliferation, but reports no new clinical findings.
16 citations
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July 2019 in “Biochemical and Biophysical Research Communications” This study concluded that CD36-expressing dermal sheath cells may influence the modulation of blood capillaries in hair follicles, potentially affecting hair cycling.
49 citations
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November 2021 in “Annual review of pathology” This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.
3 citations
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January 2018 in “Food Science and Technology Research” This study found that 6-methylsulfinylhexyl isothiocyanate (6-MSITC) significantly promoted proliferation and upregulated specific mRNA levels in human dermal papilla cells, suggesting potential as a hair growth stimulant.
6 citations
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December 2023 in “Journal of Clinical Medicine” This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.
2 citations
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January 2024 in “Proceedings of the National Academy of Sciences of the United States of America” This study developed a multiscale spatial atlas of healthy skin and basal cell carcinoma, revealing a hair follicle origin for BCC and the expansion of specific cell populations such as POSTN+ fibroblasts and RGS5+ pericytes, suggesting roles in skin cancer stroma expansion and vascular remodeling.
In this study, researchers explored how hypoxic preconditioning affects the survival and oxidative stress resilience of nestin-expressing hair follicle stem cells and SH-SY5Y neuroblastoma cells, focusing on changes in gene expression for HIF1α, BDNF, and VEGF.
8 citations
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November 2019 in “Tissue Engineering Part A” In this study, collagen scaffolds functionalized with heparin and growth factors significantly enhanced long-term skin regeneration and growth in a sheep model of fetal skin defect, suggesting potential for prenatal spina bifida treatment.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, N-MXD (minoxidil nanoparticles) was shown to deliver more drug into hair bulbs and enhance IGF-1 and VEGF levels more effectively than commercial formulations, resulting in higher therapeutic efficiency for hair growth in C57BL/6 mice.
October 2018 in “Clinical approaches and procedures in cosmetic dermatology” This source reviews the use of hyaluronic acid fillers for lip augmentation and correction, highlighting their safety and effectiveness, while noting potential adverse effects and the importance of managing complications.
October 2018 in “Vestnik dermatologii i venerologii” This study found that VEGF growth factor plays a significant role in the development of androgenetic alopecia and telogen hair loss in women, more so than KGF, TGF-01, or EGF.
January 2010 in “Seoul National University Open Repository (Seoul National University)” This review discusses the growth factors produced by adipose tissue-derived stem cells that are associated with hair growth stimulation and reports no new clinical findings.
54 citations
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September 2012 in “Acta ophthalmologica” This review highlights that various targeted cancer therapies are associated with specific ocular side-effects, emphasizing the importance of awareness among ophthalmologists for timely diagnosis and management.
8 citations
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February 2021 in “Journal of Clinical Medicine” This study found that mesenchymal stem cells sourced from hair follicle outer root sheath showed higher differentiation efficiency and angiogenic potential for vascular graft applications compared to adipose-derived stem cells.
5 citations
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January 2023 in “Cell proliferation” This study reported that supplementing rat hair follicle stem cells with chick embryo extract enhanced their migration and proliferation, possibly promoting differentiation toward Schwann cells.
June 2026 in “JAAD reviews.” This review suggests that low-dose oral minoxidil may enhance hair density in certain nonandrogenetic alopecias, but highlights the need for controlled trials due to mixed and limited evidence.
This study found that recombinant human type XVII collagen (rhCOL17A1) promotes hair growth by activating the Wnt/β-catenin and SHH/GLI signaling pathways and increasing type XVII collagen expression, with significant effects observed in both cell and mouse models.
May 2025 in “Acta Biomaterialia” This study developed microneedles combining insulin-like growth factor-1 and type XVII collagen, showing more effective hair regeneration and reduced inflammation compared to minoxidil in a mouse model of androgenetic alopecia.
February 2024 in “Molecules/Molecules online/Molecules annual” In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.
23 citations
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November 2021 in “Journal of Bionic Engineering” This study found that PCL-Col/ZnO fibrous scaffolds enhanced wound healing and exhibited antibacterial properties, making them promising for use as a wound dressing.
14 citations
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November 2012 in “SLAS discovery” This study observed that certain herbal extracts may promote hair growth and inhibit hair loss in cell lines by affecting specific protein expressions similarly to minoxidil.
5 citations
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January 2022 in “Molecular Medicine Reports” In this study, topical application of Korean maritime pine bark extract at 2% concentration significantly promoted hair growth in mice, suggesting its potential use for hair loss prevention or treatment.
4 citations
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October 2022 in “Aesthetic surgery journal” This study reports that percutaneous superficial temporal arterial hyaluronidase injection effectively treated necrosis of the frontotemporal skin and ipsilateral scalp, with patients experiencing significant recovery in skin appearance and hair regrowth 2 to 3 months after injection, following complications from hyaluronic acid filler.
2 citations
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December 2022 in “International journal of molecular sciences” This study compared RNA-seq results from horse plucked-hair and skin-biopsy samples, finding that plucked hairs were enriched with hair-follicle keratinocytes, while biopsies showed enrichment for other cell types.
1 citations
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October 2025 in “Ulusal travma dergisi” In this animal study, combined cellular therapy significantly improved diabetic wound healing, and probiotics further enhanced these effects by reducing oxidative stress, apoptosis, and inflammation while promoting vascularization and collagen organization.