5 citations
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June 2018 in “Records of Natural Products” This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.
4 citations
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December 2015 in “Journal of Medicinal Plants Research” This study reports that a 30% ethanol extract of a plant mixture enhanced hair growth in human hair dermal papilla cells and mice, suggesting potential use in hair growth products.
3 citations
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February 2021 in “Evidence-based Complementary and Alternative Medicine” This study observed that oral administration of BeauTop, a Chinese herbal medicine, significantly increased hair growth indicators, including VEGF expression, hair follicles, and hair coverage in C57BL/6 mice.
3 citations
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January 2021 in “Journal of Bioscience and Bioengineering” In this study, researchers found that sweet potato shochu oil promotes hair growth in both human follicle dermal papilla cells and C3H mice. The oil contains components like ethyl palmitate, ethyl linoleate, and ethyl α-linolenate, which were key contributors to its hair growth-inducing effects.
3 citations
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October 2022 in “Clinical, Cosmetic and Investigational Dermatology” This study found that repetitive 532 nm laser therapy significantly decreased scores for macules, pigmented, and vascular lesions on the facial area, regardless of skin phototype or age.
2 citations
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June 2025 in “International Journal of Nanomedicine” This review examines emerging biomaterial strategies designed to support both neural regeneration and cutaneous wound healing, emphasizing their potential to improve sensory function through mechanisms like axonal regrowth and vascular network formation, while noting the need for standardized assessments and clinically translatable designs.
2 citations
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November 2022 in “Scientific reports” This study found that gelatin sponges used as scaffolds in rats with deep wounds and periosteal defects enabled regeneration of diverse tissue types, including periosteum, skin, and appendages, highlighting the role of vascular niche formation.
2 citations
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October 2016 This article discusses the range of skin-related side effects caused by chemotherapy and radiotherapy, including novel patterns emerging with targeted therapies, but does not report new clinical results.
2 citations
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January 2013 in “Hair therapy & transplantation” This review discusses surgical and future therapeutic options for cicatricial alopecia and reports no clinical results; the authors emphasize the need for more options for patients without active disease signs.
2 citations
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December 2008 in “Clinical and Experimental Dermatology” This case report describes a 10-year-old girl with a cosmetically concerning forehead lesion and a history of right frontal headaches, featuring a small palpable and pulsatile erythematous lesion with associated macular erythema.
1 citations
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May 2026 in “Nature Communications” This study demonstrated that CD19-CAR T cell therapy may promote structural regeneration in the skin of systemic sclerosis patients, as evidenced by histological improvements and fibroblast population changes, suggesting its potential for tissue remodeling in fibrotic diseases.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study created a detailed spatial atlas of healthy human skin and basal cell carcinoma, revealing a potential hair follicle origin for basal cell carcinoma and expansion of certain mesenchymal cell populations.
1 citations
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January 2019 in “Journal of Embryology & Stem Cell Research” This review discusses mesenchymal stem cells' role in tissue regeneration and skin anti-aging, highlighting their migration to damaged sites and secretome effects, but reports no new clinical results.
June 2026 in “International Journal of Bioprinting” This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.
January 2026 in “International Journal of Applied Pharmaceutics” This study found that a hair tonic containing 10% mesenchymal stem cell secretome significantly increased hair density in volunteers with alopecia after eight weeks, suggesting its potential as an effective treatment option for hair growth stimulation.
January 2026 in “Journal of Epidemiology” This cross-sectional study reported that adults with greater hair loss severity had significantly higher odds of hypertension, diabetes, and cardiometabolic multimorbidity, suggesting a possible link between hair loss and cardiometabolic health.
December 2025 in “Experimental Dermatology” This study found that uric acid-linked microvascular dysfunction may play a role in alopecia areata, suggesting that targeting endothelial function and uric acid regulation could be a potential management strategy.
November 2025 in “Molecular and Cellular Biomedical Sciences” This study evaluated the effects of exosome therapy from hypoxia-treated mesenchymal stem cells on a fluconazole-induced alopecia model in rats and found that it significantly reduced TNF-α and increased VEGF levels, suggesting potential as a novel regenerative treatment for alopecia.
January 2025 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” This review highlights morphological factors contributing to age-related alopecia and suggests further research to understand and potentially mitigate cellular aging processes affecting hair quality.
March 2024 in “World Academy of Sciences Journal” This narrative review explores how exercise might help maintain skin homeostasis disrupted by protein deficiency, potentially by promoting processes like increased collagen synthesis and stimulating anti-inflammatory effects, though the exact mechanisms are not entirely understood.
November 2023 in “Food science of animal resources” This study found that in mice, oral administration of Lactilactobacillus curvatus LB-P9 accelerated hair regrowth and increased hair thickness, hair follicle numbers, and dermal thickness, likely by boosting hair growth factor production and dermal papilla proliferation.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
January 2023 in “Open veterinary journal” This study observed that applying a cream containing secretome from Bovine Umbilical Vein Endothelial Cells promoted healing and regeneration in burn wounds in rats, particularly at a 15% concentration.
June 2022 in “International journal of drug delivery technology” This study investigated the hair growth-promoting effect of topical nebivolol cream in mice, but the abstract does not provide specific results or conclusions.
July 2020 in “International Journal of Research” This review examines the development of cardiovascular risk factors related to testosterone levels in PCOS women and reports no new clinical results.
October 2019 in “Research Square (Research Square)” This study found that micro-CT imaging can effectively identify vascular structures in rat models of congenital hypospadias, providing anatomical insights for selecting preputial vessel flaps in surgical procedures.
September 2019 in “Research Square (Research Square)” In this study, micro-CT analysis revealed that severe hypospadias in finasteride-induced rats was associated with varying levels of preputial blood circulation, impacting potential surgical approaches.
This study found that topical application of Sinsun-yukza-hwan extract significantly increased hair density and thickness in a mouse alopecia model and enhanced expression of growth-related genes.
This chapter classifies various benign skin tumors and discusses their characteristics, treatment indications, and potential for recurrence, but reports no new clinical findings.
May 2016 in “Research opinions in animal & veterinary sciences” In this study, aspartame consumption during gestation in rats was associated with significant histological changes and increased apoptosis in the skin of their neonatal pups.