April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that Ginseng and Albizia extracts, when used together, protected human dermal papilla cells from oxidative stress-induced senescence, and inhibited genes that suppress hair growth, indicating their potential in preventing age-related hair density reduction.
April 2018 in “Journal of Investigative Dermatology” This study found that a water-soluble peptide from chicken egg yolk, named Hair Growth Peptide, improved hair growth in mice and female pattern hair loss through increased IGF-1 and VEGF production.
April 2018 in “Journal of Investigative Dermatology” This study found that in laboratory settings, dermal papilla cells cultured as spheroids showed significantly higher hair inductive potential and angiogenic factor expression compared to monolayer cultures.
January 2017 in “Journal of Dermatology and Venereology” This study found that Naringenin and Hesperetin significantly increased the proliferation of hair-related cells and suggested potential as natural hair growth-promoting agents.
This study revealed that IP-PA1, derived from Pantoea agglomerans, promoted hair growth in mice and increased certain growth factor expressions in human cell cultures, suggesting a unique mechanism compared to traditional hair growth treatments.
This study found that dermal papilla-like tissues derived from canine adipose stem cells promoted new hair follicle formation and increased vascularization in athymic nude mice.
This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.
January 2016 in “프로그램북(구 초록집)” In this study, LED irradiation was found to promote hORSC proliferation and stimulate the Wnt5a/β-catenin and ERK signaling pathways, suggesting a potential mechanism for hair growth.
January 2016 in “대한미용학회지” The study reported that lavender oil increased enzyme activity and cytokine expression linked to hair growth in C57BL/6 mice.
June 2015 in “Han'gug eung'yong saengmyeong hwa haghoeji/Journal of the Korean Society for Applied Biological Chemistry” This study found that several small molecule peptides based on thymosin β4 significantly promoted cell proliferation related to wound healing, angiogenesis, and hair growth more effectively than established positive controls.
April 2015 in “MOJ Cell Science & Report” This study found that rat hair follicle stem cells can be effectively transfected with VEGF 165 using lentivirus vectors, suggesting their potential use in developing tissue-engineered skin with improved vascularization.
September 2014 in “Genes and Cells” This study observed that using transfected human cord blood cells enhanced skin wound healing in rats by promoting angiogenesis and earlier termination of proliferation compared to untransfected cells.
June 2014 in “Journal of biomedical research” This study found that ethanol extract and an ethyl acetate fraction of Sargassum fusiforme promoted hair regrowth in C57BL/6 mice and stimulated expression of hair growth-related genes in both in vitro and in vivo models.
April 2014 in “동의생리병리학회지” This study found that Samhwang-Sasimtang herbal extract may enhance hair growth in mice, as indicated by increased hair follicle activity and reduced growth inhibition factors compared to a control.
February 2014 in “PubMed” This study found that Lycopersicon esculentum extracts applied to mice promoted hair growth similarly to minoxidil and increased growth factor expression, suggesting potential in hair loss treatments without skin irritation.
This study found that Chrysanthemum zawadskii extract may promote hair growth by inducing an earlier conversion of telogen to anagen and increasing the proliferation of dermal papilla cells in mice and human hair follicle cultures.
January 2014 in “Genes and Cells” This study found that transplanting human cord blood mononuclear cells transfected with a plasmid encoding VEGF and FGF2 into rat skin wounds may accelerate the wound healing process.
January 2013 in “Journal of Liaoning University of Traditional Chinese Medicine” This study found that oral administration of a ginkgo mixture increased hair growth and vascular endothelial growth factor content in C57BL/6 mice, suggesting a potential mechanism for hair growth promotion.
This study found that the methanolic heartwood extract of Avicennia marina significantly inhibited the enzyme 5 alpha-reductase type 1 in a cell-based assay, suggesting potential anti-androgenic effects for treating androgenic alopecia.
January 2013 in “프로그램북(구 초록집)” This study found that using a 0.5mm roller for microneedle therapy increased hair growth in mice and significantly affected the expression of hair growth-related molecules like VEGF.
December 2012 in “Journal of Dermatological Science” In this study, estradiol was found to increase VEGF expression in cultured dermal papilla cells at physiological levels similar to pregnancy, suggesting that declining estrogen might contribute to female pattern hair loss in older Japanese women.
December 2011 in “대한본초학회지(본초분과학회지)” In this study, Gyungohkgo-gamibang extract significantly stimulated hair growth and increased hair density and thickness in an alopecia model of C57BL/6 mice, indicating its potential as a hair growth tonic.
August 2011 in “동의생리병리학회지” This study found that acupuncture and moxibustion therapy increased hair follicle growth and enhanced the expression of several growth factors in hair follicle cycles compared to a control group.
January 2011 in “Shandong yiyao” This analysis concluded that preoperative finasteride significantly reduced blood loss during transurethral resection of the prostate by potentially decreasing the expression of VEGF and microvessel density.
July 2010 in “Journal of Investigative Dermatology” Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
This study suggests that Yonnyuniksoogobon-dan promotes hair growth in C57BL/6 mice, potentially through up-regulating EGF and VEGF and down-regulating iNOS near hair roots.
January 2010 in “Journal of Yangzhou University” In this study, sulfated fucans promoted hair growth in mice by advancing hair follicles to anagen IV and delaying their regression to catagen, possibly through VEGF and HGF effects.
January 2010 in “Seoul National University Open Repository (Seoul National University)” This review discusses the growth factors produced by adipose tissue-derived stem cells that are associated with hair growth stimulation and reports no new clinical findings.
January 2010 in “Xiandai yaowu yu linchuang” In this mouse study, Yangxue Shengfa Capsules were associated with promoted hair growth by increasing VEGF levels, hair follicle number, and skin blood vessels.
In this in vitro study, Yifa Compound Prescription was reported to enhance human hair follicle growth and increase VEGF mRNA expression compared to blank serum.